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Acute and chronic toxicity assessment of haloacetic acids using Daphnia magna

2019-10-12Journal article Restricted access
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dc.contributor.authorMelo, Armindo
dc.contributor.authorFerreira, Cláudia
dc.contributor.authorFerreira, Isabel M.P.L.V.O.
dc.contributor.authorMansilha, Catarina
dc.date.accessioned2020-05-11T18:55:12Z
dc.date.available2020-05-11T18:55:12Z
dc.date.issued2019-10-12
dc.description.abstractHaloacetic acids (HAAs) are undesirable disinfection by-products (DBPs), released into aquatic ecosystems from various anthropogenic and natural sources. The aim of this study was to examine the ecological risk of exposure to three HAAs commonly detected in water, such as monobromoacetic acid (MBA), monochloroacetic acid (MCA), and trichloroacetic acid (TCA), in in vivo acute and chronic toxicity tests using Daphnia magna as a model. Acute tests showed that MBA was the most toxic of these compounds followed by MCA and TCA as evidenced by immobilization. Aquatic organisms in natural conditions might be exposed simultaneously to numerous compounds; thus, binary mixtures of selected HAAs and a ternary mixture of these were tested. Concentration addition (CA) and independent action (IA) models were used for a predictive assessment of mixture toxicity. Data demonstrated that CA appeared to be the most reliable indicator for HAAs binary and ternary mixtures suggestive of an additive behavior. Median effective concentration (EC50) values from the mixed exposure tests were significantly lower than results obtained from single tests for all three HAAs where an increase of toxicity greater than 50%. Multigenerational chronic tests were also performed exposing daphnids to the ternary mixture of HAAs. A markedly decreased sexual maturity and number of offspring and broods per daphnid especially in the second generation were noted.pt_PT
dc.description.sponsorshipThis work received financial support from the European Union (FEDER funds POCI/01/0145/FEDER/007265) and National Funds (FCT/MEC, Fundação para a Ciência e Tecnologia and Ministério da Educação e Ciência) under the Partnership Agreement PT2020 UID/QUI/50006/2013. A. Melo wishes to thank the Fundação Ciência Tecnologia grant SFRH/BPD/86898/2012.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Toxicol Environ Health A. 2019;82(18):977-989. doi: 10.1080/15287394.2019.1676959. Epub 2019 Oct 12pt_PT
dc.identifier.doi10.1080/15287394.2019.1676959pt_PT
dc.identifier.issn1528-7394
dc.identifier.urihttp://hdl.handle.net/10400.18/6653
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor & Francispt_PT
dc.relationRISK ASSESSMENT OF DISINFECTION BY-PRODUCTS IN DRINKING WATER: OCCURRENCE, EVALUATION AND CONTROL
dc.relation.publisherversionhttps://www.tandfonline.com/doi/abs/10.1080/15287394.2019.1676959?journalCode=uteh20pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectDaphnia magnapt_PT
dc.subjectDisinfection by-productspt_PT
dc.subjectEcotoxicitypt_PT
dc.subjectHaloacetic Acidspt_PT
dc.subjectWastewaterpt_PT
dc.subjectToxicologiapt_PT
dc.titleAcute and chronic toxicity assessment of haloacetic acids using Daphnia magnapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleRISK ASSESSMENT OF DISINFECTION BY-PRODUCTS IN DRINKING WATER: OCCURRENCE, EVALUATION AND CONTROL
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FQUI%2F50006%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F86898%2F2012/PT
oaire.citation.endPage989pt_PT
oaire.citation.issue18pt_PT
oaire.citation.startPage977pt_PT
oaire.citation.titleJournal of Toxicology and Environmental Health, Part A: Current Issuespt_PT
oaire.citation.volume82pt_PT
oaire.fundingStream5876
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctDe acordo com política editorial da revista.pt_PT
rcaap.rightsembargoedAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublicationd7883dc7-6335-4f26-8bd0-e2ea4bb07c07
relation.isProjectOfPublication4f28927c-9902-4cbf-8328-358d9417daa1
relation.isProjectOfPublication.latestForDiscoveryd7883dc7-6335-4f26-8bd0-e2ea4bb07c07

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