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Anti-Aspergillus fumigatus IgG in patients with bronchiectasis and its relationship with clinical outcome

2022-11-24Journal article Open access
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dc.contributor.authorRodrigues Trápaga, Mariana
dc.contributor.authorRodrigues Poester, Vanice
dc.contributor.authorSanchotene, Karine Ortiz
dc.contributor.authorMartins Melo, Aryse
dc.contributor.authorBenelli, Jéssica Louise
dc.contributor.authorBasso, Rossana Patricia
dc.contributor.authorKlafke, Gabriel Baracy
dc.contributor.authorFernandes Ramos, Daniela
dc.contributor.authorVeríssimo, Cristina
dc.contributor.authorSabino, Raquel
dc.contributor.authorStevens, David A.
dc.contributor.authorXavier, Melissa Orzechowski
dc.date.accessioned2023-02-08T15:20:54Z
dc.date.available2023-02-08T15:20:54Z
dc.date.issued2022-11-24
dc.description.abstractAspergillosis is a mycosis, most commonly afecting the airways. This mycosis can worsen the clinical condition of patients with concurrent lung diseases. We assayed for the presence of serum anti-A. fumigatus IgG in bronchiectasis patients from a tertiary hospital in south Brazil and evaluated the relationship with clinical outcome. Thirty-one patients with bronchiec tasis, without cystic fbrosis, were included. Clinical and epidemiological data were collected from all participants. Positive serological tests were detected in 13% (4/31) of the patients. The mortality rate for the year following the assay was, in the seropositive group, 75% (3/4), whereas in the seronegative group, 15% (4/27). An illustrative case is also shown and discussed. Our study highlights the diagnostic challenge and the possible impact of Aspergillus infection on these patients, indicating the necessity of more and larger investigations in the feldpt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationArch Microbiol. 2022 Nov 24;204(12):728. doi: 10.1007/s00203-022-03345-3pt_PT
dc.identifier.doihttps://doi.org/10.1007/s00203-022-03345-3pt_PT
dc.identifier.issn0302-8933
dc.identifier.urihttp://hdl.handle.net/10400.18/8513
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerpt_PT
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s00203-022-03345-3pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAspergillosispt_PT
dc.subjectAspergillus IgGpt_PT
dc.subjectFungal Diseasept_PT
dc.subjectImmunodifusionpt_PT
dc.subjectELISApt_PT
dc.subjectInfecções Sistémicas e Zoonosespt_PT
dc.titleAnti-Aspergillus fumigatus IgG in patients with bronchiectasis and its relationship with clinical outcomept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue12pt_PT
oaire.citation.startPage728pt_PT
oaire.citation.titleArchives of Microbiologypt_PT
oaire.citation.volume204pt_PT
rcaap.embargofctAcesso de acordo com política editorial da revista.pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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