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Anti-Aspergillus fumigatus IgG in patients with bronchiectasis and its relationship with clinical outcome
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Orientador(es)
Resumo(s)
Aspergillosis is a mycosis, most commonly afecting the airways. This mycosis can worsen the clinical condition of patients
with concurrent lung diseases. We assayed for the presence of serum anti-A. fumigatus IgG in bronchiectasis patients from
a tertiary hospital in south Brazil and evaluated the relationship with clinical outcome. Thirty-one patients with bronchiec tasis, without cystic fbrosis, were included. Clinical and epidemiological data were collected from all participants. Positive
serological tests were detected in 13% (4/31) of the patients. The mortality rate for the year following the assay was, in
the seropositive group, 75% (3/4), whereas in the seronegative group, 15% (4/27). An illustrative case is also shown and
discussed. Our study highlights the diagnostic challenge and the possible impact of Aspergillus infection on these patients,
indicating the necessity of more and larger investigations in the feld
Descrição
Palavras-chave
Aspergillosis Aspergillus IgG Fungal Disease Immunodifusion ELISA Infecções Sistémicas e Zoonoses
Contexto Educativo
Citação
Arch Microbiol. 2022 Nov 24;204(12):728. doi: 10.1007/s00203-022-03345-3
Editora
Springer