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Collaborative study Brazil-Portugal - alidation of HPV lyophilized samples for the control of molecular tests

2013-10Conference object Open access
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dc.contributor.authorMenezes, Maria Elizabeth
dc.contributor.authorFedrizzi, Edson Natal
dc.contributor.authorCorrea, José Abol
dc.contributor.authorCochicho, Daniela
dc.contributor.authorMartins, Luís
dc.contributor.authorCunha, Mário
dc.contributor.authorOrnelas, Carmo
dc.contributor.authorVerdasca, Nuno
dc.contributor.authorFaria, Ana Paula
dc.date.accessioned2014-01-31T15:29:28Z
dc.date.available2014-01-31T15:29:28Z
dc.date.issued2013-10
dc.description.abstractThere are about 120 types of Human Papilloma Virus (HPV). The major importance about it is the oncogenic potential of some types. They are referred as a high and low risk for oncogenic potential. Given the importance of the disease it causes, and the use of different laboratorial techniques, mainly techniques of molecular biology, it is mandatory to have an External Quality Assurance (EQA) program base on harmonized standards that rely on consistent controls. The participation in EQA’s programs is mandatory in laboratorieswith an ISO 15189/17025 accreditation implemented. The control of Molecular Biology techniques is absolutely necessary for the quality assurance of the results, the tracking and monitorization of the performance of the reagents. However, one of its limitations is the stability, homogeneity of the material, (ISO/IEC 17043:2010 requisite) as well as the availability of control samples adequate for the parameter to be analyzed. The PNCQ, in order to fill this gap, lyophilised the HPV samples control. In order to do the validation and to test the reproducibility of these lyophilized samples, PNCQ sent to IBIOTECNO , INSA-PNAEQ -DDI and the IPOLFG-SPCLV to be analysed by different methods and reagents in two different countries and different laboratories.por
dc.identifier.urihttp://hdl.handle.net/10400.18/1902
dc.language.isoengpor
dc.publisherInstituto Nacional de Saúde Doutor Ricardo Jorge, IPpor
dc.subjectAvaliação Externa da Qualidadepor
dc.subjectAEQpor
dc.subjectPrograma Nacional de Avaliação Externa da Qualidadepor
dc.subjectPNAEQpor
dc.subjectAnálises Clínicaspor
dc.subjectBiologia Molecularpor
dc.titleCollaborative study Brazil-Portugal - alidation of HPV lyophilized samples for the control of molecular testspor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceBucharest, Romeniapor
oaire.citation.titleEQALM Symposium 2012, 10-11 Outubro 2012por
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor

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