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Estudo do tipo de Papilomavírus Humano (HPV) no aparelho genital feminino e masculino
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Advisor(s)
Abstract(s)
O diagnóstico e tipiflcação do Papiomavírus Humano foi iniciado no Laboratório de Virologia do Instituto
Nacional de Saúde em Novembro de 1990. Até Maio de 1991 foram estudadas 81 amostras prvenientes de 70
indivíduos, 57 do sexo feminino e 13 do sexo masculino, observados na Unidade de Patologia Cervico-Vulvar da
consulta de ginecologia do Hospital de St’ Maria. De entre os indivíduos do sexo feminino, 49 (86%) tinham
evidência colposcópica, histológica e/ou citológica que sugeriam infecção pelo HPV. No sexo masculino, 11
indivíduos (85%) tinham manifestações clínicas e os restantes 2 (15%) correspondiam a casos em que houve
contacto sexual com indivíduos infectados, embora até no momento não se observassem lesões aparentes.
A detecção do DNA foi positiva em 43 indivíduos (61%), dos quais 42 foram positivos para o HPV-611 1(98%) e 1
para o HPV-16 (2%). Embora preliminares, estes resultados sugerem que também entre nós a infecção genital pelo Papilomavírus Humano deve ser considerada um problema de Saúde Pública no domínio das doenças sexualmente transmissíveis.
Diagnosis and typing of HPV was started in November 1990 at the Virology department of the National Health Institute, Lisbon. Eighty one samples from 70 patients were studied, 57 from women observed at the cervico-vulvar out patient unit of the Gynecology department of Sta Maria Hospital, Lisbon, and 13 from male contacts of some of these women. Forty nine women (86%) had colposcopic, histological or cytological evidence of HPV infection. Eleven men (85%) have clinical signs of infection and 2 (15%) had had sexual intercourse with infected partners with clinical evidence of infection. HPV DNA was detected in 43 patients (61%). Forty two were infected with HPV 6/11 (98%) and one with HPV 16 (2%). These preliminary results suggest that genital infection by HPV must also be considered a public health problem in the field of sexually transmitted diseases in Portugal.
Diagnosis and typing of HPV was started in November 1990 at the Virology department of the National Health Institute, Lisbon. Eighty one samples from 70 patients were studied, 57 from women observed at the cervico-vulvar out patient unit of the Gynecology department of Sta Maria Hospital, Lisbon, and 13 from male contacts of some of these women. Forty nine women (86%) had colposcopic, histological or cytological evidence of HPV infection. Eleven men (85%) have clinical signs of infection and 2 (15%) had had sexual intercourse with infected partners with clinical evidence of infection. HPV DNA was detected in 43 patients (61%). Forty two were infected with HPV 6/11 (98%) and one with HPV 16 (2%). These preliminary results suggest that genital infection by HPV must also be considered a public health problem in the field of sexually transmitted diseases in Portugal.
Description
Keywords
Papilomavírus Humano Infecções Sexualmente Transmissíveis Virologia Saúde Pública Portugal
Pedagogical Context
Citation
Acta Med Port. 1992 Dec;5(11):567-70.