Repository logo
 
Publication

Simultaneous determination of melatonin and trans-resveratrol in wine by dispersive liquid–liquid microextraction followed by HPLC-FLD

2021-09-12Journal article Restricted access
Simple item page
dc.contributor.authorViegas, Olga
dc.contributor.authorEsteves, Cristina
dc.contributor.authorRocha, Janete
dc.contributor.authorMelo, Armindo
dc.contributor.authorFerreira, Isabel M.P.L.V.O.
dc.date.accessioned2021-04-08T10:45:22Z
dc.date.available2021-04-08T10:45:22Z
dc.date.issued2021-09-12
dc.description.abstractThe discovery of melatonin (Mel) in wines triggered a new interest in the paradigm of health benefits and wine consumption, usually ascribed to trans-resveratrol (trans-RSV). In this context, a dispersive liquid-liquid microextraction for the analysis of Mel and trans-RSV in wines by LC-FLD was developed. A 26-1 factorial design was used to identify the significant variables (p < 0.05) and Central Composite Design was used to achieve the optimal conditions: 300 µL of chloroform (extracting solvent), 1500 µL of acetonitrile (disperser solvent) and 1500 mg of NaCl (ionic strength). Excellent linearity (R2 > 0.9999), repeatability (<3.55%), and accuracy (<7.18%) were obtained using a blank matrix and recoveries (>91.9%) using wines. The method was successfully applied to the analyses of Mel (0.63-7.44 ng mL-1) and trans-RSV (169-2616 ng mL-1) in different wine varieties. Comparison with literature point the overall advantages of the new method.pt_PT
dc.description.abstractHighlights: Novel approach for simultaneous determination of melatonin and trans-resveratrol; The microextraction procedure is optimized by multivariate optimization strategy; Demonstration of the applicability of the final method in real samples; Novel method has potential for rapid analysis of melatonin and trans-resveratrol.pt_PT
dc.description.sponsorshipThis work was supported by PTDC/SAU-NUT/30322/2017 from FCT/MCTES through national funds.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFood Chem. 2021 Mar 1;339:128091. doi: 10.1016/j.foodchem.2020.128091. Epub 2020 Sep 12.pt_PT
dc.identifier.doi10.1016/j.foodchem.2020.128091pt_PT
dc.identifier.issn0308-8146
dc.identifier.urihttp://hdl.handle.net/10400.18/7668
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationDiet impac on the prevention of chronic diseases: a foodomics approach
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/abs/pii/S0308814620319531?via%3Dihubpt_PT
dc.subjectChromatography, High Pressure Liquidpt_PT
dc.subjectFood Analysispt_PT
dc.subjectLiquid Phase Microextractionpt_PT
dc.subjectMelatoninpt_PT
dc.subjectOsmolar Concentrationpt_PT
dc.subjectResveratrolpt_PT
dc.subjectSolventspt_PT
dc.subjectTime Factorspt_PT
dc.subjectWinept_PT
dc.subjectComposição dos Alimentos
dc.titleSimultaneous determination of melatonin and trans-resveratrol in wine by dispersive liquid–liquid microextraction followed by HPLC-FLDpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleDiet impac on the prevention of chronic diseases: a foodomics approach
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FSAU-NUT%2F30322%2F2017/PT
oaire.citation.startPage128091pt_PT
oaire.citation.titleFood Chemistrypt_PT
oaire.citation.volume339pt_PT
oaire.fundingStream9471 - RIDTI
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctAcesso de acordo com política editorial da revista.pt_PT
rcaap.rightsembargoedAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublication7a4cc6c5-dc89-4f3d-9f2e-b2a27dd36cd5
relation.isProjectOfPublication.latestForDiscovery7a4cc6c5-dc89-4f3d-9f2e-b2a27dd36cd5

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
66_Simultaneous.pdf
Size:
2.73 MB
Format:
Adobe Portable Document Format
Download

Collections

DSA - Artigos em revistas internacionais