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Respiratory infections in elderly people: Viral role in a resident population of elderly care centers in Lisbon, winter 2013-2014

2018-04Artigo científico Acesso aberto
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dc.contributor.authorChasqueira, Maria-Jesus
dc.contributor.authorPaixão, Paulo
dc.contributor.authorRodrigues, Maria-Lúcia
dc.contributor.authorPiedade, Cátia
dc.contributor.authorCaires, Iolanda
dc.contributor.authorPalmeiro, Teresa
dc.contributor.authorBotelho, Maria-Amalia
dc.contributor.authorSantos, Madalena
dc.contributor.authorCurran, Martin
dc.contributor.authorGuiomar, Raquel
dc.contributor.authorPechirra, Pedro
dc.contributor.authorCosta, Inês
dc.contributor.authorPapoila, Ana
dc.contributor.authorAlves, Marta
dc.contributor.authorNeuparth, Nuno
dc.date.accessioned2019-03-21T16:37:58Z
dc.date.available2019-03-21T16:37:58Z
dc.date.issued2018-04
dc.descriptionSupplementary data associated with this article can be found, in the online version, at https://doi.org/10.1016/j.ijid.2018.01.012.pt_PT
dc.description.abstractObjective: The aim of this study was to analyze the etiology and clinical consequences of viral respiratory infections in 18 elderly care centers (ECC) in Lisbon, which housed a total of 1022 residents. Methods: Nasopharyngeal swabs were collected whenever an elderly had symptoms of acute respiratory infections (ARI). PCR and RT-PCR were performed for influenza A/B, human parainfluenza virus 1–4, adenovirus, human metapneumovirus (HMPV), respiratory syncytial virus (RSV), rhinovirus, enterovirus, human coronavirus and human Bocavirus (HBoV). Array cards for atypical bacteria were also used in severe cases. Results: In total, 188 episodes of ARI were reported, being rhinovirus the most frequently detected (n = 53), followed by influenza A(H3) (n = 19) and HBoV (n = 14). Severe infections were reported in 19 patients, 11 of which were fatal, Legionela pneumophila, rhinovirus, HMPV and RSV associated with these fatalities. Nine influenza strains were analyzed, all antigenically dissimilar from vaccine strain 2013/14. “Age”, “HMPV” and “Respiratory disease” showed an association with severe infection. Conclusions: In this study an etiologic agent could be found in 60% of the acute respiratory episodes. These data provides information about the circulating viruses in ECC and highlights the importance of searching both viruses and atypical bacteria in severe ARI.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInt J Infect Dis. 2018 Apr;69:1-7. doi: 10.1016/j.ijid.2018.01.012. Epub 2018 Jan 31pt_PT
dc.identifier.doi10.1016/j.ijid.2018.01.012pt_PT
dc.identifier.issn1201-9712
dc.identifier.urihttp://hdl.handle.net/10400.18/6272
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevier/ International Society for Infectious Diseasespt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S1201971218300134?via%3Dihubpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectElderlypt_PT
dc.subjectAged, 80 and Overpt_PT
dc.subjectFemalept_PT
dc.subjectFollow-Up Studiespt_PT
dc.subjectHomes for the Agedpt_PT
dc.subjectHumanspt_PT
dc.subjectMalept_PT
dc.subjectMiddle Agedpt_PT
dc.subjectNursing Homespt_PT
dc.subjectPolymerase Chain Reactionpt_PT
dc.subjectPortugalpt_PT
dc.subjectRespiratory Tract Infectionspt_PT
dc.subjectSeasonspt_PT
dc.subjectVaccinespt_PT
dc.subjectVirus Diseasespt_PT
dc.subjectInfecções Respiratóriaspt_PT
dc.titleRespiratory infections in elderly people: Viral role in a resident population of elderly care centers in Lisbon, winter 2013-2014pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage7pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleInternational Journal of Infectious Diseasespt_PT
oaire.citation.volume69pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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