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Respiratory infections in elderly people: Viral role in a resident population of elderly care centers in Lisbon, winter 2013-2014
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Orientador(es)
Resumo(s)
Objective: The aim of this study was to analyze the etiology and clinical consequences of viral respiratory
infections in 18 elderly care centers (ECC) in Lisbon, which housed a total of 1022 residents.
Methods: Nasopharyngeal swabs were collected whenever an elderly had symptoms of acute respiratory
infections (ARI). PCR and RT-PCR were performed for influenza A/B, human parainfluenza virus 1–4,
adenovirus, human metapneumovirus (HMPV), respiratory syncytial virus (RSV), rhinovirus, enterovirus,
human coronavirus and human Bocavirus (HBoV). Array cards for atypical bacteria were also used in
severe cases.
Results: In total, 188 episodes of ARI were reported, being rhinovirus the most frequently detected
(n = 53), followed by influenza A(H3) (n = 19) and HBoV (n = 14). Severe infections were reported in 19
patients, 11 of which were fatal, Legionela pneumophila, rhinovirus, HMPV and RSV associated with these
fatalities. Nine influenza strains were analyzed, all antigenically dissimilar from vaccine strain 2013/14.
“Age”, “HMPV” and “Respiratory disease” showed an association with severe infection.
Conclusions: In this study an etiologic agent could be found in 60% of the acute respiratory episodes. These
data provides information about the circulating viruses in ECC and highlights the importance of searching
both viruses and atypical bacteria in severe ARI.
Descrição
Supplementary data associated with this article can be found, in
the online version, at https://doi.org/10.1016/j.ijid.2018.01.012.
Palavras-chave
Elderly Aged, 80 and Over Female Follow-Up Studies Homes for the Aged Humans Male Middle Aged Nursing Homes Polymerase Chain Reaction Portugal Respiratory Tract Infections Seasons Vaccines Virus Diseases Infecções Respiratórias
Contexto Educativo
Citação
Int J Infect Dis. 2018 Apr;69:1-7. doi: 10.1016/j.ijid.2018.01.012. Epub 2018 Jan 31
Editora
Elsevier/ International Society for Infectious Diseases