Publication
Genome-wide linkage analyses of quantitative and categorical autism subphenotypes
| dc.contributor.author | Liu, X.Q. | |
| dc.contributor.author | Paterson, A.D. | |
| dc.contributor.author | Szatmari, P. | |
| dc.contributor.author | Autism Genome Project Consortium | |
| dc.date.accessioned | 2011-11-30T17:22:16Z | |
| dc.date.available | 2011-11-30T17:22:16Z | |
| dc.date.issued | 2008-10-01 | |
| dc.description | Member of the Autism Genome Project Consortium: Astrid Moura Vicente | por |
| dc.description.abstract | The search for susceptibility genes in autism and autism spectrum disorders (ASD) has been hindered by the possible small effects of individual genes and by genetic (locus) heterogeneity. To overcome these obstacles, one method is to use autism-related subphenotypes instead of the categorical diagnosis of autism since they may be more directly related to the underlying susceptibility loci. Another strategy is to analyze subsets of families that meet certain clinical criteria to reduce genetic heterogeneity. | por |
| dc.identifier.citation | Biol Psychiatry. 2008 Oct 1;64(7):561-70. Epub 2008 Jul 16. | por |
| dc.identifier.issn | 0006-3223 | |
| dc.identifier.other | doi:10.1016/j.biopsych.2008.05.023 | |
| dc.identifier.uri | http://hdl.handle.net/10400.18/332 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Elsevier | por |
| dc.relation.publisherversion | http://www.sciencedirect.com/science/article/pii/S0006322308006860 | por |
| dc.subject | Autism | por |
| dc.subject | Genetic heterogeneity | por |
| dc.subject | IQ | por |
| dc.subject | Language | por |
| dc.subject | Linkage analysis | por |
| dc.subject | Schizophrenia | por |
| dc.subject | Perturbações do Desenvolvimento Infantil e Saúde Mental | por |
| dc.title | Genome-wide linkage analyses of quantitative and categorical autism subphenotypes | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 570 | por |
| oaire.citation.startPage | 561 | por |
| oaire.citation.title | Biological Psychiatry | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- Genome-wide Linkage Analyses of Quantitative and Categorical.pdf
- Size:
- 682.84 KB
- Format:
- Adobe Portable Document Format
License bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- license.txt
- Size:
- 1.71 KB
- Format:
- Item-specific license agreed upon to submission
- Description: