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earlyMYCO – a mother & child pilot study to assess early-life exposure to mycotoxins in Portugal

2021-09Conference object Restricted access
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dc.contributor.authorMartins, C.
dc.contributor.authorAssunção, R.
dc.contributor.authorCosta, A.
dc.contributor.authorSerrano, D.
dc.contributor.authorNamorado, S.
dc.contributor.authorVidigal, C.
dc.contributor.authorAlmeida, E.
dc.contributor.authorAlvito, P.
dc.contributor.authorNunes, C.
dc.date.accessioned2021-10-29T15:44:27Z
dc.date.available2021-10-29T15:44:27Z
dc.date.issued2021-09
dc.description.abstractEarly-life exposure occurs during gestation through transfer of toxic substances present in the maternal diet to the fetus and later during lactation, through the breast milk. Mycotoxins are well known carcinogenic, nephrotoxic, hepatotoxic, and immunosuppressive food chemical contaminants. Recently, human biomonitoring data revealed that Portuguese population is exposed to mycotoxins. These results emphasized the need for assessing the prenatal and lactation exposure to mycotoxins in a vulnerable period of life. The earlyMYCO project (PTDC/MED-TOX/28762/2017) aimed, for the first time, to develop and implement a pilot study to assess the early-life exposure to mycotoxins through a mother & child cohort, and to identify the associated challenges, thus contributing to the development of future studies and to the knowledge of the exposome of Portuguese population. Participants were recruited in primary health care units in Lisbon (Portugal) during pregnancy (1st trimester) and followed-up in three moments of observation: 2nd trimester of pregnancy (mother), and 1st and 6th months of the child’s life (mother & child), with the collection of biological samples (blood, urine, breast milk) and the application of sociodemographic and food consumption questionnaires (food frequency and 24h dietary recall). All the participants of the earlyMYCO pilot study (n = 19) reported more than nine years of education, with 37% reporting 10- 12 years and 63% reporting more than 12 years. Regarding the household monthly income, 42% reported a monthly income above 1941€, with most of participants (95%) being workers for remuneration or profit. Dairy products, bread, tea, and coffee were reported as the food items with higher frequency of consumption. The 24h dietary recall questionnaires confirmed these results. Detailed analysis of the data gathered allowed also to highlight the high consumption of meat, fish and vegetables. Regarding infants, 22% were fed with infant formula and 78% were exclusively breastfed. It is expected that results obtained within earlyMYCO pilot study will contribute to a deeper knowledge on exposure of vulnerable population groups (pregnant women and infants) and to the understanding of the impact of early-life exposure to mycotoxins.pt_PT
dc.description.sponsorshipThe earlyMYCO was funded by Foundation for Science and Technology (PTDC/MED-TOX/28762/2017), by CESAM (UIDP/50017/2020+UIDB/50017/2020).pt_PT
dc.description.versionN/Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/7791
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationPTDC/DTP-MEDTOX/28762/2017pt_PT
dc.relationCentre for Environmental and Marine Studies
dc.relationCentre for Environmental and Marine Studies
dc.subjectMycotoxinspt_PT
dc.subjectPregnant Womenpt_PT
dc.subjectInfantspt_PT
dc.subjectSegurança Alimentarpt_PT
dc.subjectComposição dos Alimentospt_PT
dc.subjectToxicologia dos Alimentospt_PT
dc.subjectAvaliação de Riscopt_PT
dc.subjectDeterminantes da Saúde e da Doençapt_PT
dc.subjectSaúde humanapt_PT
dc.subjectPortugal
dc.titleearlyMYCO – a mother & child pilot study to assess early-life exposure to mycotoxins in Portugalpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleCentre for Environmental and Marine Studies
oaire.awardTitleCentre for Environmental and Marine Studies
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50017%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50017%2F2020/PT
oaire.citation.conferencePlace(online)pt_PT
oaire.citation.title4th International Conference on Food Contaminants (ICFC2021): Challenges on Early-Life Exposure, 27-28 set 2021 (online)pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsclosedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isProjectOfPublication4e22de31-8fc5-4b15-b980-3fd0edf5515d
relation.isProjectOfPublication0e72e6c8-b610-43e0-931c-8ad275ad6093
relation.isProjectOfPublication.latestForDiscovery0e72e6c8-b610-43e0-931c-8ad275ad6093

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