Micronucleus and H2AX phosphorylation assessment of silica-coated iron oxide nanoparticles in human neuronal cells

http://hdl.handle.net/10400.18/3649

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Authors

Sánchez-Flores, Maria

Valdiglesias, Vanessa

Fernandez-Bertolez, Natalia

Teixeira, João Paulo

Pasaro, Eduardo

Abstract(s)

As clinically approved metal oxide nanoparticles, iron oxide nanoparticles (ION) hold immense potential in a vast variety of applications in various fields of biomedicine and biotechnology. With the increase in ION usage, particularly in diagnostics and therapeutics, concerns regarding their interactions with cellular components and possible deleterious effects are also growing.

Keywords

Iron Oxide Nanomaterials Human Neuronal Cells Nanoparticles Genotoxicidade Ambiental

URI

http://hdl.handle.net/10400.18/3649

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Establishing nanomaterial grouping/ classification strategies according to toxicity and biological effects for supporting risk assessment

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