Publication
Utility of salivary leucocytes for biomonitoring of human exposure to nanomaterials by means of the comet assay
| dc.contributor.author | Valdiglesias, Vanessa | |
| dc.contributor.author | Fernández-Bertólez, Natália | |
| dc.contributor.author | Touzani, A. | |
| dc.contributor.author | Mendéz, J. | |
| dc.contributor.author | Martinez, L. | |
| dc.contributor.author | Pásaro, E. | |
| dc.contributor.author | Reis, A.T. | |
| dc.contributor.author | Fraga, S. | |
| dc.contributor.author | Teixeira, J.P. | |
| dc.contributor.author | Costa, C. | |
| dc.contributor.author | Laffon, B. | |
| dc.date.accessioned | 2024-02-08T15:09:33Z | |
| dc.date.available | 2024-02-08T15:09:33Z | |
| dc.date.issued | 2023-06-23 | |
| dc.description.abstract | Metal-based nanoparticles (NP) are being increasingly used in a wide variety of applications in consumer products and biomedical practices. As a result, human exposure to these nanomaterials is frequent, becoming a concern to public health. Human salivary leucocytes have been proposed as a proper biological sample for the comet assay, becoming an adequate non-invasive alternative model to evaluate DNA damage. In the present study, the suitability of salivary leucocytes to respond to exposure to different nanomaterials was addressed. | pt_PT |
| dc.description.sponsorship | Xunta de Galicia (collaboration agreement "Development of research strategic actions UDC I+D+i 2021-2022: CI-CA-Disrupting Projects 2021SEM-B2 (NeuroiNPact) and 2021SEM-A1 (TOXI-NANO)”, MCIN/AEI/10.13039/501100011033 (Grant PID2020-114908GA-I00); Ministerio de Educación, Cultura y Deporte (BEAGAL18/00142, to V. Valdiglesias); (SFRH/BPD/122112/2016 to A.T. Reis) NanoBioBarriers (PTDC/MED-TOX/31162/2017) and NanoLegaTox (PO-CI-01-0145-FEDER-029651) funded by Operational Program for Competitiveness and Internationalisation through European Regional Development Funds (FEDER/FNR) and through national funds by the Portuguese Foundation for Science and Technology (FCT). | pt_PT |
| dc.description.version | N/A | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.18/9056 | |
| dc.language.iso | eng | pt_PT |
| dc.relation | A novelty study on the human uptake, genotoxicity and immunotoxicity of nanoparticles and legacy contaminants mixtures | |
| dc.subject | Metal-based Nanoparticles | pt_PT |
| dc.subject | Comet Assay | pt_PT |
| dc.subject | DNA Primary Damage | pt_PT |
| dc.subject | DNA Oxidative Damage | pt_PT |
| dc.subject | Metal Nanoparticles | pt_PT |
| dc.subject | Salivary Leucocytes | pt_PT |
| dc.subject | Genotoxicidade Ambiental | pt_PT |
| dc.subject | Biomonitoring | |
| dc.subject | Human Exposure | |
| dc.title | Utility of salivary leucocytes for biomonitoring of human exposure to nanomaterials by means of the comet assay | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | A novelty study on the human uptake, genotoxicity and immunotoxicity of nanoparticles and legacy contaminants mixtures | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F122112%2F2016/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FMED-TOX%2F31162%2F2017/PT | |
| oaire.citation.title | 12th International Symposium on Biological Monitoring in Occupational and Environmental Health (ISBM-12), 21-23 June 2023 | pt_PT |
| oaire.fundingStream | 9471 - RIDTI | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | closedAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
| relation.isProjectOfPublication | dbbc9b73-85f0-4bba-b64e-3624dc6b4d90 | |
| relation.isProjectOfPublication | 1370de00-d228-47a7-8aed-320831dc4dcd | |
| relation.isProjectOfPublication.latestForDiscovery | 1370de00-d228-47a7-8aed-320831dc4dcd |