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Research Project

Nanotechnology: Training Of Experts in Safety

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Mutagenic and carcinogenic potential of metal nanoparticles depends on their physicochemical properties
Publication . Dusinska, Maria; El Yamani, Naouale; Fjellsbø, Lise Maria; Huk, Anna; Gabelova, Alena; Alonso, Tamara Iglesias; Silva, Maria João; Pran, Elise Runden
Nanomaterials (NMs) and nanoparticles (NPs) have been studied intensively for almost two decades and still all the characteristics that might be beneficial or harmful are not explored. Although many studies have investigated the mechanisms of action of NPs in cells, results are not fully understood and in many cases are controversial. Endpoints appropriate for detecting harmful chemicals such as cytotoxicity, oxidative stress, inflammation, immunotoxicity, genotoxicity, and in some cases carcinogenicity, have been addressed. However, there might be also new mechanisms that might lead to NM-induced toxic effects.

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European Commission

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FP7

Funding Award Number

264506

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