DEP - Artigos em revistas internacionais
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- PM10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage studyPublication . Gaio, Vânia; Roquette, Rita; Monteiro, Alexandra; Ferreira, Joana; Lopes, Diogo; Dias, Carlos Matias; Nunes, BaltazarBackground: Blood lipids and glucose levels dysregulation represent potential mechanisms intermediating the adverse cardiovascular effects of ambient particulate matter (PM) exposure. This study aims to estimate the effect of long-term PM10 exposure on blood lipids and glucose levels and to assess the potential mediation and/or modification action of abdominal obesity (AO) (waist-to-height ratio). Methods: Our study was based on 2,390 participants of the first Portuguese Health Examination Survey (INSEF, 2015) with available data on blood lipids and glucose parameters and living within a 30-km radius of an air quality monitoring station with available PM10 measurements. PM10 concentrations were acquired from the air quality monitoring network of the Portuguese Environment Agency. Generalized linear models were used to assess the effect of 1-year PM10 exposure on blood lipids and glucose levels. An interaction term was introduced in the models to test the modification action of AO. Results: We found an association between PM10 and non-fasting blood triglycerides (TG) after adjustment for age, sex, education, occupation, lifestyles-related variables and temperature but only in participants with AO. Per each 1 mg/m3 PM10 increment, there was a 1.84% (95% confidence interval: 0.02–3.69) increase in TG. For the remaining blood lipid and glucose parameters, no associations were found. Conclusions: Our study demonstrates that even at low levels of exposure, long-term PM10 exposure interacts with AO to increase blood TG. Our findings suggest that reducing both AO prevalence and PM10 below current standards would result in additional health benefits for the population.
- Prevalence of abdominal obesity in the Portuguese population assessed by different anthropometric indicesPublication . Santos, Maria; Sousa-Uva, Mafalda; Namorado, Sónia; Gonçalves, Teresa; Dias, Carlos Matias; Gaio, VâniaIntroduction: Cardiovascular diseases are the leading cause of death globally. The association between abdominal obesity and cardiovascular risk is well established. This study aimed to estimate and characterize the prevalence of abdominal obesity in the Portuguese population aged 25–74 years in 2015, using waist circumference, waist to- hip ratio, waist-to-height ratio, and a body shape index. Methods: Data from the First National Health Examination Survey, a cross-sectional study, was used. Participants aged between 25 and 74 years, not pregnant, and with available data on anthropometric measurements (weight, height, waist circumference, and hip circumference) were included. Individuals undergoing cancer treatment were excluded from the study. Results: Among 4812 participants the prevalence of abdominal obesity according to each considered anthropometric measure was 40.3 % (95 % CI: 38.0–42.5), 43.6 % (95 % CI: 40.1–47.0), 65.2 % (95 % CI: 62.8–67.5) and 75.5 % (95 % CI: 74.1–76.9) when considering waist circumference, a body shape index, waist-to-hip ratio and waist-to-height ratio, respectively. The most affected individuals had 60–74 years, with no formal education or only primary education and engaged in low-skilled occupations (e.g., farmers, industrial workers, and construction workers). These findings remained consistent, regardless of the index under consideration. Conclusion: The prevalence of abdominal obesity ranged from 40.3 % for waist circumference to 75.5 % for waist-to-height ratio. Nonetheless, irrespective of the index employed, the prevalence was elevated. Older individuals, with lower education levels, and those engaged in less skilled occupations were most affected. Early identification of abdominal obesity in Primary Healthcare is essential.