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- Mercury exposure in Portuguese adolescentsPublication . Namorado, Sónia; Gomes, Diogo; Iria, Diogo; Cestelli, Federico; Mota, Afonso; Alves, Bernardo; Leal, João; Luz, Andreia; Gomes, João; Barros, Rafael; Pastorinho, M. Ramiro; Sousa, Ana C.A.The possible health effects related to exposure to hazardous chemicals have let to citizens interest in environmental health. Mercury, in particular, has been recognized as a chemical of concern, due to its well-known neurotoxicity and endocrine disrupting potential. In this work a group of teenagers from a school in Lisbon together with their teachers and researchers from the academia conducted a human biomonitoring survey on mercury levels in the students from their school. Recruitment was performed in a private school in Lisbon by a group of students from the 11th and 12th grade under the supervision of biology teachers and after having received training from researchers from the academia. All participants answered a questionnaire with specific questions on possible mercury exposure sources (e.g. seafood consumption, dental amalgams). Hair samples were collected and analysed using atomic absorption spectrometry with thermal decomposition and gold amalgamation alongside with human hair certified reference material. The study protocol was approved by the Pedagogical Board of the school and authorized by the National Data Protection Commission. From the 92 students recruited, with ages ranging from 12 to 18 years, 56.5% were females, most lived in urban areas (91.3%) and the majority (97.8%) did not have dental amalgam fillings. Participants Body Mass index (BMI) ranged from 15.1 to 28.4 kg/m2, with a mean of 20.6 ± 2.6 kg/m2. Total mercury in hair ranged from 0.01 to 3.32 μg/g, with a mean of 1.09 ± 0.66 μg/g. Around 40% of the students had mercury levels higher the US EPA reference limit of 1 μg/g, while 9.8% exhibit levels higher than the reference dose set by the WHO (2 μg/g). Levels of mercury above the US EPA reference limit are significantly associated with higher consumption of fish (more than once a week), but not with shellfish and seaweed consumption.
- Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinchPublication . O'Toole, Áine; Hill, Verity; Pybus, Oliver G.; Watts, Alexander; Bogoch, Issac I.; Khan, Kamran; Messina, Jane P.; Tegally, Houriiyah; Lessells, Richard R.; Giandhari, Jennifer; Pillay, Sureshnee; Tumedi, Kefentse Arnold; Nyepetsi, Gape; Kebabonye, Malebogo; Matsheka, Maitshwarelo; Mine, Madisa; Tokajian, Sima; Hassan, Hamad; Salloum, Tamara; Merhi, Georgi; Koweyes, Jad; Geoghegan, Jemma L.; de Ligt, Joep; Ren, Xiaoyun; Storey, Matthew; Freed, Nikki E.; Pattabiraman, Chitra; Prasad, Pramada; Desai, Anita S.; Vasanthapuram, Ravi; Schulz, Thomas F.; Steinbrück, Lars; Stadler, Tanja; Parisi, Antonio; Bianco, Angelica; García de Viedma, Darío; Buenestado-Serrano, Sergio; Borges, Vítor; Isidro, Joana; Duarte, Sílvia; Gomes, João Paulo; Zuckerman, Neta S.; Mandelboim, Michal; Mor, Orna; Seemann, Torsten; Arnott, Alicia; Draper, Jenny; Gall, Mailie; Rawlinson, William; Deveson, Ira; Schlebusch, Sanmarié; McMahon, Jamie; Leong, Lex; Lim, Chuan Kok; Chironna, Maria; Loconsole, Daniela; Bal, Antonin; Josset, Laurence; Holmes, Edward; St. George, Kirsten; Lasek-Nesselquist, Erica; Sikkema, Reina S.; Oude Munnink, Bas; Koopmans, Marion; Brytting, Mia; Sudha rani, V.; Pavani, S.; Smura, Teemu; Heim, Albert; Kurkela, Satu; Umair, Massab; Salman, Muhammad; Bartolini, Barbara; Rueca, Martina; Drosten, Christian; Wolff, Thorsten; Silander, Olin; Eggink, Dirk; Reusken, Chantal; Vennema, Harry; Park, Aekyung; Carrington, Christine; Sahadeo, Nikita; Carr, Michael; Gonzalez, Gabo; de Oliveira, Tulio; Faria, Nuno; Rambaut, Andrew; Kraemer, Moritz U.G.Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using a combination of data from routine surveillance, genomic sequencing and international travel we track the international dispersal of lineages B.1.1.7 and B.1.351 (variant 501Y-V2). We account for potential biases in genomic surveillance efforts by including passenger volumes from location of where the lineage was first reported, London and South Africa respectively. Using the software tool grinch (global report investigating novel coronavirus haplotypes), we track the international spread of lineages of concern with automated daily reports, Further, we have built a custom tracking website (cov-lineages.org/global_report.html) which hosts this daily report and will continue to include novel SARS-CoV-2 lineages of concern as they are detected.