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- Exposure of the Portuguese adult population to arsenic: preliminary results of a human biomonitoring studyPublication . Namorado, Sónia; Coelho, Inês; Ventura, Marta; Gueifão, Sandra; Rego, Andreia; Castanheira, Isabel; Alves Alves, Clara; Castilho, Emília; Cordeiro, Eugénio; Dinis, Ana; Gouveia, Bruna; Prokopenko, Tamara; Vargas, Patrícia; Silva, Susana; Gaio, Vânia; Nunes, Baltazar; Matias Dias, CarlosBACKGROUND AND AIM:Although arsenic is an element naturally present in the environment, it is highly toxic in its inorganic forms. Exposure can occur through consumption of drinking water and contaminated food. Long-term exposure was shown to be associated with negative health outcomes. Nevertheless, data on the Portuguese population’s exposure to arsenic is scarce. As such, the aim of this work was to assess the exposure to Arsenic in the Portuguese population using samples collected in the study "Exposure of the Portuguese Population to Environmental Chemicals: a study nested in INSEF 2015" (INSEF-ExpoQuim), developed as an aligned study of the European Human Biomonitoring Initiative (HBM4EU). METHODS: INSEF-ExpoQuim was an epidemiologic study nested in INSEF 2015 including 270 participants aged 28-39 years,living in Portugal for more than 12 months and able to follow an interview in Portuguese. Fieldwork was developed between June 2019 and February 2020. First morning urine samples were collected along with data on socio-demographic characteristics, living conditions and residential history, habits/lifestyle, nutrition, health, occupation and substance specific information covering nearly all exposure pathways. Procedures followed the guidelines of the HBM4EU project. Total urinary arsenic is currently being determined by inductively coupled plasma mass spectrometry. RESULTS:Preliminary results for 38 samples yielded total urinary arsenic concentrations ranging from 11 to 462 μg/L with an average of 86 ± 94 μg/L. After completion of the determination of the urinary arsenic levels for all the samples a complete analysis of the data will be performed. CONCLUSIONS:Results from this study will contribute to the knowledge on the Portuguese population’s exposure to arsenic and may support the development and implementation of policy measures aimed at minimizing exposure to this chemical and improving the health of the population.
- HBM4EU-MOM: intervene to raise awareness to specific dietary recommendations and reduceprenatal mercury exposurePublication . Namorado, Sónia; Assunção, Ricardo; Santiago, Susana; Esteban López, Marta; Dominguez Morueco, Noelia; Ingi Halldórsson, Þórhallur; Jacobsen, Eva; Gabriel, Catherine; Karakitsios, Spyros; Giannadaki, Despina; Xatjipanagi, Adamos; Anastasi, Elena; Thoma, Chrysanthi; Snoj Tratnik, Janja; Horvat, Milena; Sarigiannis, Denis; Katsonouri, AndromachiBACKGROUND AND AIM:Mercury and its compounds are toxic and are among the substances of higher concern globally.Toxicity depends on mercury compounds, route of exposure and duration. The European population is mostly exposed to organic mercury (methylmercury) due to fish consumption; while exposure to inorganic and elemental mercury is largely associated with dental amalgams, accidental spills of elemental mercury and food produced in contaminated sites. Previous studies have shown that mercury levels in European population are higher in countries with higher fish consumption.However, because of the beneficial nutrients they provide, fish are an essential component of the human diet. In order to reduce exposure and avoid adverse health effects, it is extremely important to balance the risks and benefits of eating fish,especially in vulnerable groups such as pregnant women. Most European countries do not have official guidelines for the consumption of fish during pregnancy, and even if these guidelines exist, they are often not communicated to pregnant women in an appropriate way. As such, under the European Human Biomonitoring Initiative (HBM4EU) an intervention study – HBM4EU-MOM – is being developed in five European countries with high fish consumption (Cyprus, Greece, Iceland, Portugal, Spain) to help reduce prenatal exposure to mercury,while ensuring the nutritional benefits of fish by developing and raising awareness to specific recommendations for fish consumption during pregnancy. METHODS:This presentation will highlight the work already performed, including the harmonized development of the intervention and support materials to be implemented in the five countries. RESULTS:Preliminary results on the implementation of the developed intervention and its evaluation using Human Biomonitoring will also be presented. CONCLUSIONS:This study's results will support the definition of policies to protect human health in vulnerable populations. HBM4EU has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 733032.