Browsing by Issue Date, starting with "2013-10-24"
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- Sistema Nacional de Gestão de Dados - "Alimentos PT.ON.DATA". Características técnicas e funcionalidadesPublication . Pereira, João; Tomé, Sidney; Oliveira, Luisa
- Genetic variation in a gene involved in glycosphingolipid lipid biosynthesisPublication . Amaral, Olga; Duarte, Ana Joana; Pinto, Eugenia; Ribeiro, I.; Lopes, Lurdes; Ribeiro, DiogoIn this work we presented the identification and distribution of genetic variations among the control samples studied. The results obtained with the different samples showed the existence of several polymorphic changes. Polymorphisms in the UGCG gene may interfere with the amount of substrate available for degradation in specific diseases along the same pathway. Thus,the degree of genetic variability might influence the phenotypic expression as well as the lysosomal burden. Conclusion: Assessment of variation in the UGCG gene should be considered, particularly in patients who do not comply with the expected genotype/phenotype correlations.
- Occupational exposure to aflatoxin b1 in swine production and possible contamination sourcesPublication . Viegas, S.; Veiga, L.; Figueiredo, P.; Almeida, A.; Carolino, E.; Sabino, R.; Verissimo, C.Although the adverse health consequences of ingestion of food contaminated with aflatoxin B1 (AFB1) are known, relatively few studies are available on the adverse effects of exposure in occupational settings. Taking this into consideration, our study was developed aiming to elucidate the possible effects of occupational exposure to AFB1 in Portuguese swine production facilities using a specific biomarker to assess exposure to AFB1. In total, 28 workers participated in this study, providing blood samples, and a control group (n = 30) was composed of subjects without any type of agricultural activity. Fungal contamination was also studied by conventional methods through air, surfaces, and new and used floor coverage. Twenty-one workers (75%) showed detectable levels of AFB1 with values ranging from <1 ng/ml to 8.94 ng/ml and with a mean value of 1.91 ± 1.68 ng/ml. In the control group, the AFB1 values were all below 1 ng/ml. Twelve different Aspergillus species were identified. Aspergillus versicolor presented the highest airborne spore counts (3210 CFU/m3) and was also detected in higher values in surfaces (>300 CFU/cm2). Data indicate that exposure to AFB1 occurs in swine barns, and this site serves as a contamination source in an occupational setting.