Browsing by Author "Pasaro, Eduardo"
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- Genotoxic potential of nanomaterials: in vitro evaluation of iron oxide nanoparticlesPublication . Valdiglesias, Vanessa; Fernández-Bertólez, Natalia; Kiliç, Gozde; Costa, Carla; Costa, Solange; Teixeira, João Paulo; Pasaro, Eduardo; Laffon, BlancaThe rapidly growing industrial and medica! use of nanomaterials, particularly metal oxide nanoparticles, has led to growing concern about their toxicity. Moreover, human beings are commonly exposed to their potential harmful effects since these nanomaterials are frequently present in a number of industrial products of very regular use. Among them, iron oxide nanoparticles (ION) have been widely used in various biomedical applications, for both diagnosis and therapy, due to their unique magnetic properties.
- Micronucleus and H2AX phosphorylation assessment of silica-coated iron oxide nanoparticles in human neuronal cellsPublication . Sánchez-Flores, Maria; Valdiglesias, Vanessa; Kiliç, Gozde; Costa, Carla; Fernandez-Bertolez, Natalia; Costa, Solange; Teixeira, João Paulo; Pasaro, Eduardo; Laffon, BlancaAs clinically approved metal oxide nanoparticles, iron oxide nanoparticles (ION) hold immense potential in a vast variety of applications in various fields of biomedicine and biotechnology. With the increase in ION usage, particularly in diagnostics and therapeutics, concerns regarding their interactions with cellular components and possible deleterious effects are also growing.