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Browsing by Author "Oliveira, A.C."

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  • Poly-resistant tuberculosis outbreak in Northern Portugal: a nine year tale
    Publication . Gomes, B.; Molina-Correa, G.; Neves-Reina, L.; Oliveira, A.C.; Macedo, R.; Carvalho, C.; Correia, A.M.
    Extract: In 2017, the notification rate of tuberculosis in the Northern Region of Portugal was 21.1 cases per 100 000 inhabitants. According to the National Tuberculosis Programme Surveillance System (SVIG-TB), poly-resistance to isoniazid and streptomycin (PR-HS) represented 2.6–5% of the cases notified in the Northern Region between 2009 and 2017 Although they represent a relatively low proportion of cases in Portugal, poly-resistances such as PR-HS are precursors to multidrug resistance and, consequently, should be closely monitored.
    2020-12Journal article Open access Show more
  • Serological and molecular evidence of Bartonella henselae in cats from Luanda city, Angola
    Publication . Barradas, P.F.; De Sousa, R.; Vilhena, H.; Oliveira, A.C.; Luz, M.F.; Granada, S.; Cardoso, L.; Lopes, A.P.; Gonçalves, H.; Mesquita, J.R.; Ferreira, P.; Amorim, I.; Gärtner, F.
    A total of 100 domestic cats from Luanda (Angola) were tested for the presence of antibodies against Bartonella henselae and spotted fever group of Rickettsia (SFGR) using indirect immunofluorescence assay (IFA). Molecular screening targeting the riboflavin synthase (ribC) gene for Bartonella and outer membrane protein B (ompB) gene for Rickettsia, using conventional PCR and sequencing was also performed in cat´s blood samples. Sixty-six percent of the cats from Luanda had IgG antibodies against Bartonella species but none of them had antibodies against SFGR. Of the total seroreactive cats for Bartonella henselae, 4.5% had an IgG titre of 64 (cut-off), 60.6% a titre of 128, 28.8% a titre of 256 and 6.1% a titre of 512. A statistically significant association was observed between seropositivity for Bartonella henselae and the lack of access to prophylaxis against ectoparasites (p = 0.018). Molecular detection and further sequence analysis of the positive amplicons allowed identification of Bartonella henselae in a 2-year old male cat. To the best of our knowledge this study confirms for the first time, the presence of Bartonela henselae circulating in domestic cats from Luanda. This fact call the attention for the possible cases of cat-scratch disease in humans.
    2019-04-14Journal article Restricted access Show more