Browsing by Author "Nascimento, P."
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- First Case of Tularemia Reported in Portugal: Probably of Imported OriginPublication . Lopes de Carvalho, I.; Nascimento, P.; Núncio, M.S.; Rico, M.T.Tularemia is a zoonotic disease caused by Francisella tularensis, a gram-negative, facultative intracellular bacterium. Typically, human and animal infections are caused by F. tularensis subspecies tularensis (type A) strains mainly in Canada and USA, and F. tularensis subspecies holarctica (type B) strains throughout the northern hemisphere, including Europe. Tularemia is a disease with epidemiological surveillance in Europe since 2003 (Decision 2000/96/EC). Despite being considered an uncommon disease, recent outbreaks have been reported in several countries, including Spain, France, Scandinavia, Balkans and Hungary, and sporadic cases in Austria, Italy and the United Kingdom. In spite offbeing a disease of compulsory declaration in Portugal since 2003, until now no human cases were reported. In Portugal, seroprevalence rate of high-risk population is 8.9% and F. tularensis subsp. holarctica was first detected in 2007 by molecular methods in a human sample. Since 1998, National Institute of Health has provided the laboratory diagnosis of this disease, following the occurrence of an epidemic outbreak in Spain. The authors report here the first case of ulceroglandular form of tularemia in Portugal, probably of imported origin.
- Primeiro caso de Tularémia de importação em PortugalPublication . Nascimento, P.; Rico, M.T.; Roque, R.; De Sousa, R.; Núncio, M.S.; Lopes de Carvalho, I.A tularémia é uma zoonose causada pela bactéria Francisella tularensis, que se transmite ao homem por contacto directo com animais infectados, artrópodes, ar, água ou alimentos contaminados. Apesar de ser pouco frequente na Europa, têm sido notificados surtos recentes (Espanha,França,Escandinávia,Balcãs e Hungria) e casos esporádicos (Áustria,Itália e Reino Unido). Em Portugal, F. tularensis subsp. holarctica foi detectada pela primeira vez em 2007. A F. tularensis pode infetar o homem através da pele, inalação, mucosas e via gastrointestinal. O estabelecimento desta infeção depende da porta de entrada e do número de organismos. As principais apresentações de doença incluem as formas ulceroglandular, glandular, oculoglandular, orofaríngea, pneumónica e tífica.