A carregar...
Publicação
Quaternary mixtures of TiO2NP, CeO2NP, arsenic, and mercury potentiate A549, HepG2 and SH-SY5Y cells cytotoxicity
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 422.26 KB | Adobe PDF |
Orientador(es)
Resumo(s)
Introduction: Nanoparticles (NP) released to the environment interact with pre-existing contaminants, potentially leading to cytotoxicity and raising concerns regarding human safety to co- exposure to multiple chemicals. This work assesses and compares viability of A549, HepG2 and SH-SY5Y cells after short (24h; WST-1 assay) and long-term (7 days; clonogenic assay) exposure to single and quaternary mixtures of: titanium dioxide nanoparticles (TiO2NP) 0.75; 75 mg/L; cerium oxide nanoparticles (CeO2NP) 0.1; 10 μg/L; arsenic (As) 0.01; 0.75; 2.5 mg/L; and mercury (Hg) 0.5; 10; 20 mg/L. Mixtures were divided in four groups: low, mid-low, mid- high and high.
Descrição
Palavras-chave
Nanotoxicity Mixtures Titanium Dioxide Nanoparticles Nanoparticles Cytotoxicity Genotoxicidade Ambiental