Neuropsychiatric disease (NPD) clustering in families with Autism Spectrum Disorder (ASD): genetic, epigenetic and environmental issues

Marques, Ana Rita; Martiniano, Hugo; Romão, Luísa; M. Vicente, Astrid

http://hdl.handle.net/10400.18/4848

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
Ana_Rita_Marques_BioSys_Poster_Jan_2017.pdf		2.72 MB	Adobe PDF	Download

Send Feedback

Authors

Abstract(s)

Objectives: The aim of this project is to understand the role of epigenetic factors in ASD, with a particular focus on long noncoding lncRNA, miRNA and other regulatory molecules. For this purpose this project has two main specific objectives: 1. To identify lncRNA and miRNA loci implicated in ASD through the analysis of two large datasets with CNV and SNV data from ASD families and controls; 2. To identify genetic variants and modulating epigenetic factors that could lead to differential disease expression by exploring multiplex families in which ASD co-occurs with other NPDs.

Keywords

Autism Spectrum Disorder Perturbações do Desenvolvimento Infantil e Saúde Mental

URI

http://hdl.handle.net/10400.18/4848

Publisher

Instituto Nacional de Saúde Doutor Ricardo Jorge, IP

Collections

DPSPDNT - Posters/abstracts em congressos nacionais

Full item page