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Unavoided cerebral palsy after induced hypothermia

2025-11Documento de conferência Acesso aberto
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datacite.subject.fosCiências Médicas
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorMoreira , Tânia
dc.contributor.authorFolha, Teresa
dc.contributor.authorVirella, Daniel
dc.contributor.authorPrograma de Vigilância Nacional da Paralisia Cerebral
dc.date.accessioned2026-02-25T09:29:53Z
dc.date.available2026-02-25T09:29:53Z
dc.date.issued2025-11
dc.description.abstractInduced hypothermia (IH) reduces the risk of death or cerebral palsy (CP) among term neonates with moderate-to-severe hypoxic-ischemic encephalopathy (HIE). It is now accepted as the standard of care. The aim of the study is intend to access if the severity of CP among survivors of HIE after IH is similar to their counterparts not submitted to IH or otherwise. Data from Portuguese Surveillance of Cerebral Palsy registers 5 to 8-year-old children with CP, born in Portugal between 2010-2016 ≥ 36 weeks gestation and andmitted into the neonatal care unit. From 2967 registered children with CP, 790 were identified as been born in Portugal between 2010 and 2016. From 86 eligible children (42 born 2010-12, 44 born 2013-16), 35 (42%) had been on IH. Overall, children with CP, if had been on IH had higher prevalence of Dyskinetic CP 57% vs 35%; p 0.04; GMFCS III-V 80% vs 56.5%; p 0.03; MACS II-V 85% vs 62%; p 0.04. Increased CP complexity: 0 indicators 10% vs 16%; 1-2 indicators 33% vs 51%; 3-4 indicators 57% vs 32%; p 0.057 No differences were found on the prevalences of epilepsy, higher grade affection on Viking SS or cognition and schooling. Children of the 2013-2016 cohort, compared with the 2010-2012 cohort did not reveal significant improvement in any of the clinical or functionality parameters. Instead, a tendency for a higher prevalence of GMFCS III-V was found (p 0.066). Children with CP, if having been on IH, seem to be more likely to have high complexity CP. Surveillance data provide useful information on the effectiveness IH to prevent CP after HIE.eng
dc.identifier.urihttp://hdl.handle.net/10400.18/10989
dc.language.isoeng
dc.peerreviewedn/a
dc.rights.uriN/A
dc.subjectCerebral Palsy
dc.subjectInduced Hypothermia
dc.subjectSeverity of Cerebral Palsy
dc.subjectParalisia Cerebral
dc.subjectEstados de Saúde e de Doença
dc.titleUnavoided cerebral palsy after induced hypothermiaeng
dc.title.alternativeSistematic monitoring of effectiveness is neededpor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferenceDate2025-11
oaire.citation.conferencePlacePorto, Portugal
oaire.citation.title10th International Neonatology Association Conference (INAC), 6-9 November 2025
oaire.versionhttp://purl.org/coar/version/c_b1a7d7d4d402bcce

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