Serious fungal infections in Portugal

Sabino, Raquel; Verissímo, Cristina; Brandão, João; Martins, C.; Alves, D.; Pais, C.; Denning, D. W.

Publication

Serious fungal infections in Portugal

2017-07Journal article

dc.contributor.author	Sabino, Raquel
dc.contributor.author	Verissímo, Cristina
dc.contributor.author	Brandão, João
dc.contributor.author	Martins, C.
dc.contributor.author	Alves, D.
dc.contributor.author	Pais, C.
dc.contributor.author	Denning, D. W.
dc.date.accessioned	2018-03-01T11:01:17Z
dc.date.available	2018-08-01T00:30:13Z
dc.date.issued	2017-07
dc.description.abstract	There is a lack of knowledge on the epidemiology of fungal infections worldwide because there are no reporting obligations. The aim of this study was to estimate the burden of fungal disease in Portugal as part of a global fungal burden project. Most published epidemiology papers reporting fungal infection rates from Portugal were identified. Where no data existed, specific populations at risk and fungal infection frequencies in those populations were used in order to estimate national incidence or prevalence, depending on the condition. An estimated 1,510,391 persons develop a skin or nail fungal infection each year. The second most common fungal infection in Portugal is recurrent vulvovaginal candidiasis, with an estimated 150,700 women (15-50 years of age) suffering from it every year. In human immunodeficiency virus (HIV)-infected people, oral or oesophageal candidiasis rates were estimated to be 19.5 and 16.8/100,000, respectively. Candidaemia affects 2.19/100,000 patients, in a total of 231 cases nationally. Invasive aspergillosis is less common than in other countries as chronic obstructive pulmonary disease (COPD) is uncommon in Portugal, a total of 240 cases annually. The estimated prevalence of chronic pulmonary aspergillosis after tuberculosis (TB) is 194 cases, whereas its prevalence for all underlying pulmonary conditions was 776 patients. Asthma is common (10% in adults) and we estimate 16,614 and 12,600 people with severe asthma with fungal sensitisation and allergic bronchopulmonary aspergillosis, respectively. Sixty-five patients develop Pneumocystis pneumonia in acquired immune deficiency syndrome (AIDS) and 13 develop cryptococcosis. Overall, we estimate a total number of 1,695,514 fungal infections starting each year in Portugal.	pt_PT
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.citation	Eur J Clin Microbiol Infect Dis. 2017 Jul;36(7):1345-1352. doi: 10.1007/s10096-017-2930-y. Epub 2017 Feb 10	pt_PT
dc.identifier.doi	10.1007/s10096-017-2930-y	pt_PT
dc.identifier.issn	0934-9723
dc.identifier.uri	http://hdl.handle.net/10400.18/5098
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.publisher	Springer Verlag	pt_PT
dc.relation.publisherversion	https://dx.doi.org/10.1007/s10096-017-2930-y	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by-nc/4.0/	pt_PT
dc.subject	Fungal Burden	pt_PT
dc.subject	Portugal	pt_PT
dc.subject	Aspergilosis	pt_PT
dc.subject	Candidemia	pt_PT
dc.subject	ABPA	pt_PT
dc.subject	CPA	pt_PT
dc.subject	Human Immunodeficiency Virus	pt_PT
dc.subject	Chronic Obstructive Pulmonary Disease	pt_PT
dc.subject	Fungal Infection	pt_PT
dc.subject	Invasive Aspergillosis	pt_PT
dc.subject	Invasive Fungal Infection	pt_PT
dc.subject	Infecções Sistémicas e Zoonoses	pt_PT
dc.subject	Infecções Respiratórias
dc.title	Serious fungal infections in Portugal	pt_PT
dc.type	journal article
dspace.entity.type	Publication
oaire.citation.endPage	1352	pt_PT
oaire.citation.issue	7	pt_PT
oaire.citation.startPage	1345	pt_PT
oaire.citation.title	European Journal of Clinical Microbiology and Infectious Diseases	pt_PT
oaire.citation.volume	36	pt_PT
rcaap.rights	embargoedAccess	pt_PT
rcaap.type	article	pt_PT