Zika virus infections imported to Portugal, the National Reference Laboratory experience: The importance of sample collection time lapse in diagnosis

Zé-Zé, L.M.; Alves, M.J.

http://hdl.handle.net/10400.18/4304

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Authors

Zé-Zé, L.M.

Alves, M.J.

Abstract(s)

Zika virus (ZIKV) belongs to the genus Flavivirus and was first isolated from the blood of a febrile sentinel rhesus monkey during a study of yellow fever in 1947, in Zika Forest, Uganda. ZIKV is transmitted by Aedes sp. Mosquitoes, as Dengue, Yellow fever and Chikungunya viruses, and was until recently considered a mild pathogenic mosquito-borne flavivirus with very few reported human cases of self-limiting acute febrile illnesses most often with maculopapular rash, headache, malaise and conjunctivitis, all followed by full recovery without sequel. During 60 years, cases of ZIKV infections were detected only sporadically in Africa, and South and Southeast Asia. (...)