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Characterizing stakeholders in cancer primary prevention in European countries: an exploration of challenges and opportunities using a penta-helix framework

datacite.subject.fosCiências Médicas::Ciências da Saúde
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorRoxo, Luis
dc.contributor.authorCarvalho da Silva Santos, Ana João
dc.contributor.authorGirvalaki, Charis
dc.contributor.authorGeantă, Marius
dc.contributor.author4P-CAN WP2 study team
dc.contributor.authorSousa Uva, Mafalda
dc.date.accessioned2026-01-20T12:38:01Z
dc.date.available2026-01-20T12:38:01Z
dc.date.issued2025-07-16
dc.description4P-CAN WP2 study team: Mirjana Babamova, Adriana Boată, Stefania Boccia, Ana Cristina Garcia, Stanimir Hasardzhiev, Andreia Leite, Lilia Kriachkova, Milica Kuzmanoska, Nikola Milasevic, Vlad Nerau, Ivaylo Petrov, Ramona Popescu, Oscar Ribeiro, Viktor Semenov, Leonardo Villani, Ivana Vojvodic, Clara Volintiru, Rodica Milena Zaharia, Serhii Zakharov.
dc.descriptionThis article is part of the Research Topic: Empowering Community Stakeholders: Novel Approaches to Address Health Inequities.
dc.description.abstractObjectives: Cancer incidence has been increasing in Europe, with stark disparities between Western and Eastern regions. Cancer primary prevention (CPP) is a cost-effective strategy tackling lifestyle and risk factor exposure, but its implementation goes beyond the actions of the governments. This study aims to characterize stakeholders’ role in CPP, using a penta-helix approach, with the objective of shedding a new light in the Iron Curtain of Cancer Cases. Methods: We followed a mixed-methods approach, with quantitative and qualitative data from CPP stakeholders from the public sector, academia/research, private sector, media and civil society. Snowball sampling was used to distribute a survey where participants (n = 110) were asked which sector was the main driver of change, the most proactive and the most influential. Purposive sampling was used for semi-structured interviews (n = 33), where stakeholders were asked about their CPP activities, motivations, barriers and opportunities, and the role of other sectors. Countries were coded as Western or Eastern. Descriptive analysis was used for quantitative data, while thematic analysis was used for qualitative data. Results: The public sector is viewed as the main driver of change, and the most proactive and influential in both Western and Eastern Europe. However, Eastern European countries emphasize the role of other sectors in CPP more strongly. Thematic analysis identified key roles and themes for the public sector (Strategy: “Looking after citizen’s health,” “Making the system work,” “Operational Engagement”), academia/research (Knowledge: “Scientific credibility,” “Diversity of approaches,” “Getting out of the lab,” “Life in academia/research”), private sector (Responsibility: “Profit-oriented,” “Resources and operational activities,” “Ethics and responsibility”), media (Dissemination: “Capacity to reach people,” “Diversity and scope,” “Information and dissemination”) and civil society (Engagement: “Proximity to people,” “Advocacy and voice,” “Do what others do not do”). Although no meaningful differences were identified between Western and Eastern countries, the results highlight opportunities for Eastern countries to reduce regional disparities. Conclusion: Overall, results point to the complementary role of the sectors, emphasizing that involving different stakeholders and promoting adequate collaborations between them is crucial to unravel the full potential of CPP.eng
dc.description.sponsorship4P-CAN is funded by the European Union, HORIZON-MISS-2022-CANCER-01-01 (Project ID 101104432).
dc.identifier.citationFront Public Health. 2025 Jul 16:13:1550712. doi: 10.3389/fpubh.2025.1550712. eCollection 2025
dc.identifier.doi10.3389/fpubh.2025.1550712
dc.identifier.eissn2296-2565
dc.identifier.pmid40740378
dc.identifier.urihttp://hdl.handle.net/10400.18/10720
dc.language.isoeng
dc.peerreviewedyes
dc.publisherFrontiers Media
dc.relationPersonalized CANcer Primary Prevention research through Citizen Participation and digitally enabled social innovation
dc.relation.hasversionhttps://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1550712/full
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject4P-CAN
dc.subjectPrimary prevention
dc.subjectCancer
dc.subjectEurope
dc.subjectMixed-Methods
dc.subjectStakeholders
dc.subjectDeterminantes da Saúde e da Doença
dc.subjectEuropeeng
dc.titleCharacterizing stakeholders in cancer primary prevention in European countries: an exploration of challenges and opportunities using a penta-helix frameworkeng
dc.typejournal article
dcterms.referenceshttps://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1550712/full#SM1
dspace.entity.typePublication
oaire.awardTitlePersonalized CANcer Primary Prevention research through Citizen Participation and digitally enabled social innovation
oaire.awardURIhttp://hdl.handle.net/10400.18/10689
oaire.citation.startPage1550712
oaire.citation.titleFrontiers in Public Health
oaire.citation.volume13
oaire.fundingStreamHORIZON Research and Innovation Actions
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameCarvalho da Silva Santos
person.familyNameSousa Uva
person.givenNameAna João
person.givenNameMafalda
person.identifier.ciencia-id7E12-E842-1216
person.identifier.orcid0000-0003-0556-5513
person.identifier.orcid0000-0002-7910-3111
relation.isAuthorOfPublication7b015568-111e-4298-94af-90f1d3a958e4
relation.isAuthorOfPublication25d0f118-6569-4c2e-b997-053d764204c5
relation.isAuthorOfPublication.latestForDiscovery7b015568-111e-4298-94af-90f1d3a958e4
relation.isProjectOfPublication6f321517-ff58-473c-af52-1f5c57e7e6b6
relation.isProjectOfPublication.latestForDiscovery6f321517-ff58-473c-af52-1f5c57e7e6b6

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