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Urinary cotinine levels and environmental tobacco smoke in mothers and children of Romania, Portugal and Poland within the European human biomonitoring pilot study

2015-08Journal article Restricted access
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dc.contributor.authorLupsa, Ioana-Rodica
dc.contributor.authorNunes, Baltazar
dc.contributor.authorLigocka, Danuta
dc.contributor.authorElena Gurzau, Anca
dc.contributor.authorJakubowski, Marek
dc.contributor.authorCasteleyn, Ludwine
dc.contributor.authorAerts, Dominique
dc.contributor.authorBiot, Pierre
dc.contributor.authorDen Hond, Elly
dc.contributor.authorCastaño, Argelia
dc.contributor.authorEsteban, Marta
dc.contributor.authorKolossa-Gehring, Marike
dc.contributor.authorFiddicke, Ulrike
dc.contributor.authorKnudsen, Lisbeth E.
dc.contributor.authorSchoeters, Greet
dc.contributor.authorFátima Reis, M.
dc.date.accessioned2016-03-01T16:53:36Z
dc.date.available2019-01-01T01:30:10Z
dc.date.issued2015-08
dc.description.abstractThe aim of this study was to explore data from the DEMOCOPHES study population for Romania, Portugal and Poland, in order to assess smoking patterns and the extent of ETS exposure and compare the national study samples with reference to the respective anti-smoking laws. The subset of the DEMOCOPHES study sample consisted of 360 children and their mothers (120 in each of the three countries - Romania (RO), Portugal (PT) and Poland (PL). Smoking was assessed using a detailed questionnaire for the participants, which addresses both active and passive smoking. This assessment uses exposure-relevant questionnaire data, in particular on the home environment and residence, socio-demographic characteristics, lifestyle such as nutrition, smoking behavior, other exposure-relevant behavior and occupational history, as well as urinary cotinine and creatinine measurements. We performed general statistical analysis and innovative receiver operating characteristic (ROC) curve analyses. Smoking prevalence as evaluated by the questionnaire was generally high, and higher than official statistics, which suggests some under-reporting in the countries, particularly in Romania. Urinary cotinine levels provided biochemical confirmation of the high and similar smoking prevalence for the three countries. Concerning ETS exposure, Romania presented significantly higher levels, for children as well as for non-smoking mothers, with Portugal showing significantly lower levels. Compared to non-smoking mothers, the children showed relatively higher ETS exposure levels in all three countries. The established country-specific optimal cut-off values in urinary cotinine to distinguish smokers from non-smokers vary more than those to discriminate ETS exposure extent in non-smoking mothers and children. Although different between countries, these values are a valuable output to monitor effectiveness of both national antismoking laws and educational programs in the three countries. The findings of this study point to the urgent need for stronger, more effective and well enforced smoke-free legislation in the three countries.pt_PT
dc.description.sponsorshipDEMOCOPHES received funding through the LIFE þ financial instrument of the European Commision (DGENV), as well as through funding received from different national institutions of the DEMOCOPHES countries (http://www.eu-hbm.info/demo- cophes/project-partners).pt_PT
dc.identifier.citationEnviron Res. 2015 Aug;141:106-17. doi: 10.1016/j.envres.2015.03.018. Epub 2015 Apr 1pt_PT
dc.identifier.doi10.1016/j.envres.2015.03.018pt_PT
dc.identifier.issn0013-9351
dc.identifier.urihttp://hdl.handle.net/10400.18/3556
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationEuropean coordination action on human biomonitoring
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S0013935115000961pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectAntismoking Legislationpt_PT
dc.subjectCut-off valuept_PT
dc.subjectEnvironmental Tobacco Smokept_PT
dc.subjectHuman Biomonitoringpt_PT
dc.subjectUrinary Cotininept_PT
dc.subjectDeterminantes da Saúde e da Doençapt_PT
dc.subjectObservação em Saúde e Vigilânciapt_PT
dc.titleUrinary cotinine levels and environmental tobacco smoke in mothers and children of Romania, Portugal and Poland within the European human biomonitoring pilot studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleEuropean coordination action on human biomonitoring
oaire.awardURIinfo:eu-repo/grantAgreement/EC/FP7/244237/EU
oaire.citation.endPage117pt_PT
oaire.citation.startPage106pt_PT
oaire.citation.titleEnviromental Researchpt_PT
oaire.citation.volume141pt_PT
oaire.fundingStreamFP7
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameEuropean Commission
rcaap.rightsembargoedAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublication39483d70-d33a-45d6-a465-8250f239c33f
relation.isProjectOfPublication.latestForDiscovery39483d70-d33a-45d6-a465-8250f239c33f

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