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Synergistic effect of the homologous PB1–NA gene constellation in Influenza A virus reassortants: Evaluation and characterization of reassortant influenza variant viruses cross-resistant to influenza Neuraminidase Inhibitors
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Orientador(es)
Resumo(s)
This project aims to elucidate the functional impact of specific mutation induced changes in the
NA and PB1 genes on the viral fitness and cross-resistance profile of A(H1N1)pdm09 viruses.
Descrição
Palavras-chave
Viral Fitness Reverse Genetics A(H1N1)pdm09 Viruses Cross-resistance Profile