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Nanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effects

2020-05Journal article Restricted access
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dc.contributor.authorBessa, Maria João
dc.contributor.authorBrandão, Fátima
dc.contributor.authorViana, Mar
dc.contributor.authorGomes, João F.
dc.contributor.authorMonfort, Eliseo
dc.contributor.authorCassee, Flemming R.
dc.contributor.authorFraga, Sónia
dc.contributor.authorTeixeira, João Paulo
dc.date.accessioned2020-04-28T20:42:58Z
dc.date.available2020-04-28T20:42:58Z
dc.date.issued2020-05
dc.description.abstractThe ceramic industry is an industrial sector of great impact in the global economy that has been benefiting from advances in materials and processing technologies. Ceramic manufacturing has a strong potential for airborne particle formation and emission, namely of ultrafine particles (UFP) and nanoparticles (NP), meaning that workers of those industries are at risk of potential exposure to these particles. At present, little is known on the impact of engineered nanoparticles (ENP) on the environment and human health and no established Occupational Exposure Limits (OEL) or specific regulations to airborne nanoparticles (ANP) exposure exist raising concerns about the possible consequences of such exposure. In this paper, we provide an overview of the current knowledge on occupational exposure to NP in the ceramic industry and their impact on human health. Possible sources and exposure scenarios, a summary of the existing methods for evaluation and monitoring of ANP in the workplace environment and proposed Nano Reference Values (NRV) for different classes of NP are presented. Case studies on occupational exposure to ANP generated at different stages of the ceramic manufacturing process are described. Finally, the toxicological potential of intentional and unintentional ANP that have been identified in the ceramic industry workplace environment is discussed based on the existing evidence from in vitro and in vivo inhalation toxicity studies.pt_PT
dc.description.sponsorshipThis work was supported by the Portuguese Foundation for Science and Technology (FCT) through the ERA-NET SIINN project CERASAFE (SIINN/0004/2014). M.J. Bessa and F. Brandão are recipients of FCT PhD scholarships (SFRH/BD/120646/2016 and SFRH/BD/101060/2014) under the framework of Programa Operacional Capital Humano (POCH) and European Union fundingpt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationEnviron Res. 2020 May;184:109297. doi: 10.1016/j.envres.2020.109297. Epub 2020 Feb 24pt_PT
dc.identifier.doi10.1016/j.envres.2020.109297pt_PT
dc.identifier.issn0013-9351
dc.identifier.urihttp://hdl.handle.net/10400.18/6542
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevier/ Academic Presspt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/abs/pii/S0013935120301900?via%3Dihubpt_PT
dc.subjectAirborne Nanoparticlespt_PT
dc.subjectCeramic Industrypt_PT
dc.subjectHuman Healthpt_PT
dc.subjectOccupational Exposurept_PT
dc.subjectToxicitypt_PT
dc.subjectGenotoxicidade Ambiental
dc.titleNanoparticle exposure and hazard in the ceramic industry: an overview of potential sources, toxicity and health effectspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/ERA-SIINN%2F0004%2F2013/PT
oaire.citation.startPage109297pt_PT
oaire.citation.titleEnvironmental Researchpt_PT
oaire.citation.volume184pt_PT
oaire.fundingStream3599-PPCDT
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctDe acordo com política editorial da revista.pt_PT
rcaap.rightsembargoedAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublication495635f6-42e0-4841-a433-b0a9d5834a1c
relation.isProjectOfPublication.latestForDiscovery495635f6-42e0-4841-a433-b0a9d5834a1c

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