Publication
Antimicrobial susceptibility and oxymino-β-lactam resistance mechanisms in Salmonella enterica and Escherichia coli isolates from different animal sources
| dc.contributor.author | Clemente, Lurdes | |
| dc.contributor.author | Manageiro, Vera | |
| dc.contributor.author | Jones-Dias, Daniela | |
| dc.contributor.author | Correia, Ivone | |
| dc.contributor.author | Themudo, Patricia | |
| dc.contributor.author | Albuquerque, Teresa | |
| dc.contributor.author | Geraldes, Margarida | |
| dc.contributor.author | Matos, Filipa | |
| dc.contributor.author | Almendra, Cláudia | |
| dc.contributor.author | Ferreira, Eugénia | |
| dc.contributor.author | Caniça, Manuela | |
| dc.date.accessioned | 2016-03-22T17:37:41Z | |
| dc.date.available | 2020-01-01T01:30:10Z | |
| dc.date.issued | 2015 | |
| dc.description | These results were partially presented at the 3rd ASM Conference on Antimicrobial Resistance in Zoonotic Bacteria and Foodborne Pathogens in Animals, Humans and the Environment, 26e29 June 2012, Aix-la-Provence and at TEMPH (Trends in Environmental Microbiology for Public Health), 18e21 September 2014, Lisbon. | pt_PT |
| dc.description.abstract | The impact of extended-spectrum β-lactamases (ESBLs) and plasmid-mediated AmpC β-lactamases (PMAβs) of animal origin has been a public health concern. In this study, 562 Salmonella enterica and 598 Escherichia coli isolates recovered from different animal species and food products were tested for antimicrobial resistance. Detection of ESBL-, PMAβ-, plasmid-mediated quinolone resistance (PMQR)-encoding genes and integrons was performed in isolates showing non-wild-type phenotypes. Susceptibility profiles of Salmonella spp. isolates differed according to serotype and origin of the isolates. The occurrence of cefotaxime non-wild-type isolates was higher in pets than in other groups. In nine Salmonella isolates, blaCTX-M (n = 4), blaSHV-12 (n = 1), blaTEM-1 (n = 2) and blaCMY-2 (n = 2) were identified. No PMQR-encoding genes were found. In 47 E. coli isolates, blaCTX-M (n = 15), blaSHV-12 (n = 2), blaCMY-2 (n = 6), blaTEM-type (n = 28) and PMQR-encoding genes qnrB (n = 2), qnrS (n = 1) and aac(6')-Ib-cr (n = 6) were detected. To the best of our knowledge, this study is the first to describe the presence of blaCMY-2 (n = 2) and blaSHV-12 (n = 1) genes among S. enterica from broilers in Portugal. This study highlights the fact that animals may act as important reservoirs of isolates carrying ESBL-, PMAβ- and PMQR-encoding genes that might be transferred to humans through direct contact or via the food chain. | pt_PT |
| dc.description.sponsorship | V. Manageiro and D. Jones-Dias were supported by grants SFRH/BPD/77486/2011 and SFRH/BD/80001/2011, respectively, from the Fundação para a Ciência e Tecnologia, Lisbon, Portugal. | pt_PT |
| dc.identifier.citation | Res Microbiol. 2015 Sep;166(7):574-83. doi: 10.1016/j.resmic.2015.05.007. Epub 2015 Jun 5. | pt_PT |
| dc.identifier.doi | 10.1016/j.resmic.2015.05.007 | pt_PT |
| dc.identifier.issn | 0923-2508 | |
| dc.identifier.uri | http://hdl.handle.net/10400.18/3723 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Elsevier/Institut Pasteur | pt_PT |
| dc.relation.publisherversion | http://www.sciencedirect.com/science/article/pii/S0923250815000972 | pt_PT |
| dc.subject | Resistência aos Antibióticos | pt_PT |
| dc.subject | Salmonella enterica | pt_PT |
| dc.subject | Escherichia coli | pt_PT |
| dc.subject | ESBL | pt_PT |
| dc.subject | PMAβ | pt_PT |
| dc.subject | PMQR | pt_PT |
| dc.title | Antimicrobial susceptibility and oxymino-β-lactam resistance mechanisms in Salmonella enterica and Escherichia coli isolates from different animal sources | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 583 | pt_PT |
| oaire.citation.startPage | 574 | pt_PT |
| oaire.citation.title | Research in Microbiology | pt_PT |
| oaire.citation.volume | 166(7) | pt_PT |
| rcaap.rights | embargoedAccess | pt_PT |
| rcaap.type | article | pt_PT |