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Effectiveness of XBB.1.5 Vaccines Against Symptomatic SARS‐CoV‐2 Infection in Older Adults During the JN.1 Lineage‐Predominant Period, European VEBIS Primary Care Multicentre Study, 20 November 2023–1 March 2024

2024-11-10Journal article Open access
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dc.contributor.authorMerdrignac, Lore
dc.contributor.authorLaniece Delaunay, Charlotte
dc.contributor.authorVerdasca, Nuno
dc.contributor.authorVega‐Piris, Lorena
dc.contributor.authorO'Donnell, Joan
dc.contributor.authorSève, Noémie
dc.contributor.authorTrobajo‐Sanmartín, Camino
dc.contributor.authorBuda, Silke
dc.contributor.authorHooiveld, Mariëtte
dc.contributor.authorRodrigues, Ana Paula
dc.contributor.authorTúri, Gergő
dc.contributor.authorLatorre‐Margalef, Neus
dc.contributor.authorMlinarić, Ivan
dc.contributor.authorLazar, Mihaela
dc.contributor.authorMaurel, Marine
dc.contributor.authorCastrillejo, Daniel
dc.contributor.authorBennett, Charlene
dc.contributor.authorRameix‐Welti, Marie‐Anne
dc.contributor.authorMartínez‐Baz, Iván
dc.contributor.authorDürrwald, Ralf
dc.contributor.authorMeijer, Adam
dc.contributor.authorMelo, Aryse
dc.contributor.authorOroszi, Beatrix
dc.contributor.authorHagey, Tove Samuelsson
dc.contributor.authorKurečić Filipović, Sanja
dc.contributor.authorDijkstra, Frederika
dc.contributor.authorGómez, Verónica
dc.contributor.authorBacci, Sabrina
dc.contributor.authorKaczmarek, Marlena
dc.contributor.authorKissling, Esther
dc.contributor.authorVEBIS Primary Care Vaccine Effectiveness Group
dc.date.accessioned2025-03-11T14:52:04Z
dc.date.available2025-03-11T14:52:04Z
dc.date.issued2024-11-10
dc.descriptionMapear com DDIpt_PT
dc.description.abstractWe estimated XBB.1.5 vaccine effectiveness (VE) against symptomatic SARS-CoV-2 infection among adults aged ≥65 years during the 2023/2024 JN.1 lineage-predominant period in a European multi-country test-negative case–control study at primary care level. We estimated VE adjusted by study site, age, sex, chronic conditions and onset date. We included 220 cases and 1733 controls. The VE was 48% (95% CI: 12–71), 23% (95% CI: −11–48) and 5% (95% CI: −92–56) among those with symptom onset 1–5, 6–11, and ≥12weeks after vaccination, respectively. XBB.1.5 vaccine provided short and moderate protection against JN.1 symptomatic infection.pt_PT
dc.description.sponsorshipFunding for this project was received from the European Centre for Disease Prevention and Control (ECDC) implementing Framework Contract ECDC/2021/019 ‘Vaccine effectiveness, burden and impact of COVID-19 and influenza’.
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInfluenza Other Respir Viruses . 2024 Nov;18(11):e70009. doi: 10.1111/irv.70009
dc.identifier.doi10.1111/irv.70009pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/10432
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.relationECDC/2021/019pt_PT
dc.relation.hasversionhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11551475/
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/doi/10.1111/irv.70009pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCOVID-19pt_PT
dc.subjectSARS-CoV-2pt_PT
dc.subjectCase–control Studypt_PT
dc.subjectTest-negative Designpt_PT
dc.subjectVaccine Effectivenesspt_PT
dc.subjectPrimary Carept_PT
dc.subjectMulti-country Studypt_PT
dc.subjectInvestigação em Serviços de Saúdept_PT
dc.titleEffectiveness of XBB.1.5 Vaccines Against Symptomatic SARS‐CoV‐2 Infection in Older Adults During the JN.1 Lineage‐Predominant Period, European VEBIS Primary Care Multicentre Study, 20 November 2023–1 March 2024pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage8pt_PT
oaire.citation.issue11pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleInfluenza and Other Respiratory Virusespt_PT
oaire.citation.volume18pt_PT
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameVerdasca
person.familyNameRodrigues
person.familyNameGOMEZ TEIXEIRA PINTO
person.givenNameNuno
person.givenNameAna Paula
person.givenNameVERÓNICA DEL PILAR
person.identifier.ciencia-id7B1B-27D1-22F6
person.identifier.ciencia-idFA1B-D68F-2611
person.identifier.orcid0000-0002-4673-5411
person.identifier.orcid0000-0003-2264-4723
person.identifier.orcid0000-0003-0485-0005
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication55f513ae-19d8-45a0-81b0-be0864f4b9b1
relation.isAuthorOfPublicationc23c6d96-e605-424f-abbb-64d783c73939
relation.isAuthorOfPublicationeae04cda-2c73-437b-8666-6593d03aa34d
relation.isAuthorOfPublication.latestForDiscoveryc23c6d96-e605-424f-abbb-64d783c73939

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