Publicação
A multi-stakeholder perspective on Barriers to the adoption of personalized prevention in European healthcare systems
| datacite.subject.fos | Ciências Médicas | |
| dc.contributor.author | Costa, Alexandra | |
| dc.contributor.author | Cardoso, Maria Luís | |
| dc.contributor.author | Carvalho, Adriana Reimão | |
| dc.contributor.author | Osti, Tommaso | |
| dc.contributor.author | Farina, Sara | |
| dc.contributor.author | Taha, Abdelrahman | |
| dc.contributor.author | Savoia, Cosimo | |
| dc.contributor.author | Russo, Luigi | |
| dc.contributor.author | Maio, Alessandra | |
| dc.contributor.author | Scarsi, Nicolò | |
| dc.contributor.author | Flodkvist, Evelina | |
| dc.contributor.author | Gyllenberg, Alexandra | |
| dc.contributor.author | Boccia, Stefania | |
| dc.contributor.author | Vicente, Astrid Moura | |
| dc.date.accessioned | 2026-10-02T11:26:56Z | |
| dc.date.available | 2026-10-02T11:26:56Z | |
| dc.date.issued | 2026-06-24 | |
| dc.description.abstract | Introduction: Personalized prevention is an important component of personalized medicine, tailoring interventions to the biological, behavioral, sociocultural and environmental characteristics of individuals for the prevention of disease onset, progression and recurrence. Despite its potential, personalized preventive interventions (PPI) remain less commonly implemented in clinical practice. This study explored the main barriers to a broader adoption of PPI in European healthcare systems. Methods: A multi-stakeholder consultation involving citizens/patients, health professionals, researchers, and policymakers was conducted using a sequential mixed-methods approach. In the first phase, semi-structured interviews with key informants representing different stakeholder groups were conducted. The thematic analysis of interview findings, complemented by insights from a review of the literature, informed the development of an online survey implemented in the second phase of the study. Twenty-six interviews and 270 complete surveys were analyzed. Stakeholders identified barriers across three main domains: (1) healthcare systems, (2) implementation, and (3) awareness, education, and literacy. Key barriers associated with limited PPI adoption included the predominant focus of health strategies on treatment over prevention, unresolved ethical, legal, and social issues (ELSI), limited awareness and knowledge of personalized prevention among both professionals and citizens, and the lack of appropriate cost–benefit evaluation models. Findings highlight interconnected barriers that may impact a broader PPI adoption across healthcare system, governance, implementation, and awareness-related domains. Continued stakeholder dialogue and engagement, alongside efforts to address awareness and governance-related challenges, may support the broader integration of PPI into European healthcare systems. | eng |
| dc.description.sponsorship | This work was supported by the European Union’s Horizon Europe Research and Innovation Program (Grant agreement No.101057721). | |
| dc.identifier.citation | Front Public Health. 2026;14:14:1817705. doi: 10.3389/fpubh.2026.1817705 | |
| dc.identifier.doi | 10.3389/fpubh.2026.1817705 | |
| dc.identifier.eissn | 2296-2565 | |
| dc.identifier.pmid | 42422673 | |
| dc.identifier.uri | http://hdl.handle.net/10400.18/11374 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | |
| dc.publisher | Frontiers Media | |
| dc.relation | A PeRsOnalized Prevention roadmap for the future HEalThcare | |
| dc.relation.hasversion | https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2026.1817705/full | |
| dc.relation.ispartof | Frontiers in Public Health | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | Clinical Practice | |
| dc.subject | Genetics | |
| dc.subject | Interventions | |
| dc.subject | Non-communicable diseases | |
| dc.subject | Personalized Prevention | |
| dc.subject | Europe | |
| dc.subject | Políticas de Saúde | |
| dc.title | A multi-stakeholder perspective on Barriers to the adoption of personalized prevention in European healthcare systems | eng |
| dc.type | journal article | |
| dcterms.references | https://public-pages-files-2025.frontiersin.org/articles/1817705/file/Supplementary_file_1.docx/1817705_supplementary-file_1/2 | |
| dspace.entity.type | Publication | |
| oaire.awardNumber | 101057721 | |
| oaire.awardTitle | A PeRsOnalized Prevention roadmap for the future HEalThcare | |
| oaire.awardURI | http://hdl.handle.net/10400.18/10568 | |
| oaire.citation.startPage | 1817705 | |
| oaire.citation.title | Frontiers in Public Health | |
| oaire.citation.volume | 14 | |
| oaire.fundingStream | HORIZON Coordination and Support Actions | |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |
| relation.isProjectOfPublication | 916c464a-f8c8-451d-82c1-71fd2a13a6f0 | |
| relation.isProjectOfPublication.latestForDiscovery | 916c464a-f8c8-451d-82c1-71fd2a13a6f0 |