Cyanara cardunculus L. by-products as a sustainable  source of bioactive compounds for industrial applications

Barbosa, Cássia H.; Andrade, Mariana A.; Duarte, Maria Paula; Mateus, Ana Rita; Vilarinho, Fernanda; Fernando, Ana Luísa; Sanches Silva, Ana

Publicação

Cyanara cardunculus L. by-products as a sustainable source of bioactive compounds for industrial applications

2025-09-03Documento de conferência

datacite.subject.fos	Ciências Agrárias::Biotecnologia Agrária e Alimentar
datacite.subject.sdg	03:Saúde de Qualidade
dc.contributor.author	Barbosa, Cássia H.
dc.contributor.author	Andrade, Mariana A.
dc.contributor.author	Duarte, Maria Paula
dc.contributor.author	Mateus, Ana Rita
dc.contributor.author	Vilarinho, Fernanda
dc.contributor.author	Fernando, Ana Luísa
dc.contributor.author	Sanches Silva, Ana
dc.date.accessioned	2026-02-09T15:28:00Z
dc.date.available	2026-02-09T15:28:00Z
dc.date.issued	2025-09-03
dc.description.abstract	Cynara cardunculus L. (cardoon) is a versatile perennial crop that thrives in challenging environments with high productivity. Its flowers are valued for their coagulating properties in cheesemaking, while its leaves, rich in bioactive compounds, are normally discarded. This study aimed to assess the antioxidant and antimicrobial potential of ethanolic and methanolic extracts from fresh and dried cultivated cardoon var. altilis DC leaves (FCC and DCC, respectively) to evaluate the impact of oven-drying with forced air circulation on the bioactive profile of the leaves. Dried cultivated cardoon leaf extracts exhibited stronger antioxidant activity than fresh leaf extracts, although fresh leaves contained a greater variety of polyphenolic compounds. Among the 16 identified compounds, chlorogenic acid, apigenin, and luteolin were the most abundant. The best antioxidant activity was observed in dried leaf extracts for both methanolic (EC50 = 0.8 mg/mL, AAC = 279.67) and ethanolic (EC50 = 2.1 mg/mL, AAC = 448.06) solvents. Regarding antimicrobial properties, Gram-positive bacteria showed higher sensitivity to both ethanolic and methanolic extracts compared to Gram-negative bacteria. The dried leaf ethanolic extract demonstrated stronger antimicrobial activity, with lower minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values (125–2000 μg/mL) across most tested microorganisms. Dried leaf extracts exhibited better antimicrobial efficacy than fresh leaf extracts, although only mild inhibition was observed against Aspergillus fumigatus. In conclusion, the findings suggest that dried cardoon leaves are a valuable by-product as a source of bioactive compounds for various industrial applications, particularly in the food industry, as well as in cosmetic and pharmaceutical industries. In this sense, the use of active compounds obtained from cardoon leaves is aligned with the concepts of circular economy and sustainability. More specifically, it is aligned with the United Nations Sustainable Development Goal 12, Ensure sustainable consumption and production patterns. This approach promotes both environmental and economic sustainability by transforming high-value by-products into innovative applications.	eng
dc.description.sponsorship	Cássia H. Barbosa would like to express gratitude for the Ph.D. scholarship from Fundação para a Ciência e Tecnologia (FCT)—2021.08154.BD (https://doi.org/10.54499/2021.08154.BD) 2023.15813.PEX.
dc.identifier.uri	http://hdl.handle.net/10400.18/10867
dc.language.iso	eng
dc.peerreviewed	yes
dc.relation	Mechanical Engineering and Resource Sustainability Center
dc.relation	Mechanical Engineering and Resource Sustainability Center
dc.relation	Center for the Study of Animal Science
dc.relation	Exploring Cardoon (Cynara cardunculus L.) by-products to obtain cutting-edge Active Packaging for food applications
dc.relation	2021.08154.BD
dc.rights.uri	N/A
dc.subject	Cardoon
dc.subject	Antimicrobial Properties
dc.subject	Antioxidant Properties
dc.subject	Circular Economy
dc.subject	Chlorogenic Acid
dc.subject	Segurança Alimentar
dc.title	Cyanara cardunculus L. by-products as a sustainable source of bioactive compounds for industrial applications	eng
dc.type	conference object
dspace.entity.type	Publication
oaire.awardTitle	Mechanical Engineering and Resource Sustainability Center
oaire.awardTitle	Mechanical Engineering and Resource Sustainability Center
oaire.awardTitle	Center for the Study of Animal Science
oaire.awardTitle	Exploring Cardoon (Cynara cardunculus L.) by-products to obtain cutting-edge Active Packaging for food applications
oaire.awardURI	info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04077%2F2020/PT
oaire.awardURI	info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04077%2F2020/PT
oaire.awardURI	info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00211%2F2020/PT
oaire.awardURI	http://hdl.handle.net/10400.18/10790
oaire.awardURI	info:eu-repo/grantAgreement/FCT/OE/2021.08154.BD/PT
oaire.citation.conferenceDate	2025-09-03
oaire.citation.conferencePlace	Funchal, Madeira, Portugal
oaire.citation.title	7th International Conference on Wastes: Solutions, Treatments and Opportunities, 3-5 September 2025
oaire.fundingStream	6817 - DCRRNI ID
oaire.fundingStream	6817 - DCRRNI ID
oaire.fundingStream	6817 - DCRRNI ID
oaire.fundingStream	Concurso de Projetos Exploratórios em Todos os Domínios Científicos 2023
oaire.fundingStream	OE
oaire.version	http://purl.org/coar/version/c_970fb48d4fbd8a85
project.funder.identifier	http://doi.org/10.13039/501100001871
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project.funder.identifier	http://doi.org/10.13039/501100001871
project.funder.name	Fundação para a Ciência e a Tecnologia
project.funder.name	Fundação para a Ciência e a Tecnologia
project.funder.name	Fundação para a Ciência e a Tecnologia
project.funder.name	Fundação para a Ciência e a Tecnologia
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