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Biological toxins detection: a rapid diagnosis in an emergency response

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dc.contributor.authorLopes de Carvalho, I.
dc.contributor.authorCordeiro, R.
dc.contributor.authorSaraiva, M.
dc.contributor.authorCunha, I.C.
dc.contributor.authorPelerito, A.
dc.contributor.authorNúncio, M.S.
dc.date.accessioned2018-03-07T16:25:29Z
dc.date.available2018-03-07T16:25:29Z
dc.date.issued2017-01
dc.description.abstractToxins are chemical substances of biological origin, and they can be considered chemical or biological warfare agents. Four toxins are included in the list of bioterrorism agents: botulinum toxin (BoNT), saxitocin, ricin, and staphylococcal enterotoxin B. BoNT is included in Category A, while the other 3 are considered Category B. Botulism is a potentially fatal disease caused solely by the action of serologically distinct neurotoxins (BoNT/A, /B, /C, /D, /E, /F/ or /G) that prevent acetylcholine release at neuromuscular junctions, resulting in paralysis. The Emergency Response and Biopreparedness Unit is the Portuguese national reference laboratory for biological events or catastrophes and has skilled professionals, know-how, Biosafety Level (BSL)-3 facilities, capacity to work 24 hours per day, 7 days per week, and trained human resources to increase lab capacity in emergency situations. The laboratory diagnosis capacity includes the detection of bacteria, viruses, and toxins that are considered bioterrorism agents, using microbiology, immunology, and molecular biology techniques. Participation in European projects such as EquaTox allowed the upgrade of biosafety procedures and technical skills and the implementation of the best techniques to detect the biological toxins that can be used as biological weapons.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/5308
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectBiopreparednesspt_PT
dc.subjectBotulinum neurotoxinspt_PT
dc.subjectToxinspt_PT
dc.subjectSegurança Alimentarpt_PT
dc.subjectInfecções Sistémicas e Zoonosespt_PT
dc.titleBiological toxins detection: a rapid diagnosis in an emergency responsept_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceMadrid, Españapt_PT
oaire.citation.titleTOXINS 2017 - Basic Science and Clinical Aspects of Botulinum and Other Neurotoxins, 18-21 January 2017pt_PT
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT

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