Publication
Candida auris in Intensive Care Setting: The First Case Reported in Portugal
| dc.contributor.author | Henriques, João | |
| dc.contributor.author | Mixão, Verónica | |
| dc.contributor.author | Cabrita, Joana | |
| dc.contributor.author | Duarte, Tiago Isidoro | |
| dc.contributor.author | Sequeira, Tânia | |
| dc.contributor.author | Cardoso, Sofia | |
| dc.contributor.author | Germano, Nuno | |
| dc.contributor.author | Dias, Liliana | |
| dc.contributor.author | Bento, Luís | |
| dc.contributor.author | Duarte, Sílvia | |
| dc.contributor.author | Veríssimo, Cristina | |
| dc.contributor.author | Gomes, João Paulo | |
| dc.contributor.author | Sabino, Raquel | |
| dc.date.accessioned | 2024-02-14T09:23:29Z | |
| dc.date.available | 2024-02-14T09:23:29Z | |
| dc.date.issued | 2023-08-09 | |
| dc.description | (This article belongs to the Special Issue Genomic Epidemiology of Fungal Diseases 2023) | pt_PT |
| dc.description.abstract | Candida auris is an opportunistic human pathogen that has rapidly spread to multiple countries and continents and has been associated with a high number of nosocomial outbreaks. Herein, we report the first case of C. auris in Portugal, which was associated with a patient transferred from Angola to an ICU in Portugal for liver transplantation after a SARS-CoV-2 infection. C. auris was isolated during the course of bronchoalveolar lavage, and it was subjected to antifungal susceptibility testing and whole-genome sequence analysis. This isolate presents low susceptibility to azoles and belongs to the genetic clade III with a phylogenetic placement close to African isolates. Although clade III has already been reported in Europe, taking into account the patient’s clinical history, we cannot discard the possibility that the patient’s colonization/infection occurred in Angola, prior to admission in the Portuguese hospital. Considering that C. auris is a fungal pathogen referenced by WHO as a critical priority, this case reinforces the need for continuous surveillance in a hospital setting | pt_PT |
| dc.description.sponsorship | This work was supported by funding from the European Union EU4Health Programme under grant agreement no. 101113460 (GENEO) and by national funds through the Foundation for Science and Technology (FCT), I.P., under Individual CEEC 2022.00851.CEECIND/CP1748/CT0001. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | J Fungi (Basel). 2023 Aug 9;9(8):837. doi: 10.3390/jof9080837. | pt_PT |
| dc.identifier.doi | 10.3390/jof9080837 | pt_PT |
| dc.identifier.issn | 2309-608X | |
| dc.identifier.uri | http://hdl.handle.net/10400.18/9095 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | MDPI | pt_PT |
| dc.relation | PathoGenSurveil - building dynamic workflows towards a sustainable and efficient genomics-informed pathogen surveillance | |
| dc.relation.publisherversion | https://www.mdpi.com/2309-608X/9/8/837 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Candida auris | pt_PT |
| dc.subject | Whole-genome Sequencing | pt_PT |
| dc.subject | Antifungal Resistances | pt_PT |
| dc.subject | Infecções Sistémicas e Zoonoses | pt_PT |
| dc.subject | Resistência aos Antimicrobianos | pt_PT |
| dc.subject | Portugal | pt_PT |
| dc.title | Candida auris in Intensive Care Setting: The First Case Reported in Portugal | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | PathoGenSurveil - building dynamic workflows towards a sustainable and efficient genomics-informed pathogen surveillance | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/CEEC IND5ed/2022.00851.CEECIND%2FCP1748%2FCT0001/PT | |
| oaire.citation.issue | 8 | pt_PT |
| oaire.citation.startPage | 837 | pt_PT |
| oaire.citation.title | Journal of Fungi | pt_PT |
| oaire.citation.volume | 9 | pt_PT |
| oaire.fundingStream | CEEC IND5ed | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.embargofct | Acesso de acordo com política editorial da revista. | pt_PT |
| rcaap.embargofct | Acesso de acordo com política editorial da revista. | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isProjectOfPublication | cd3d705e-d6dd-4bf1-8b0e-0e3e0abc0b43 | |
| relation.isProjectOfPublication.latestForDiscovery | cd3d705e-d6dd-4bf1-8b0e-0e3e0abc0b43 |