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Characterization of a Population Concerning Vitamins and Anemia Biomarkers

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dc.contributor.authorMota, Carla
dc.contributor.authorTavares, Nuno
dc.contributor.authorTorres, Duarte
dc.contributor.authorSantos, Mariana
dc.contributor.authorCastanheira, Isabel
dc.contributor.authorMatos, Ana Sofia
dc.date.accessioned2014-11-26T16:44:41Z
dc.date.available2014-11-26T16:44:41Z
dc.date.issued2014-09
dc.descriptionAbstract publicado em:"Book of Abstracts",(nº100).por
dc.description.abstractFolate, vitamin B12, iron and hemoglobin are essential for metabolic functions. Deficiency of these can cause several known pathologies and, untreated, severe morbidity and death. The objective of this study is to characterize a population, concerning serum levels of folate, B12, iron and hemoglobin, as well as finding evidence of correlations between these parameters and illnesses, mainly cardiovascular, gastrointestinal, neurological and anemia. The laboratorial data collected consists of blood analysis in patients, required by the patients’ doctors, and were retrieved in 2012. The total population consisted of 728 individuals, residing in Lisbon metropolitan area in Portugal. When coming in for examination, the patients were asked routine questions about their age, gender, county of residence, reason for examination and what medication or supplementation they were taking. The population consisted of 140 male patients and 588 female patients, aged from 2 to 95 years of age. There are 329 persons over 60 years old, these are considered elderly patients. Clinical data was submitted to multivariate analysis. The data was screened with Spearman correlation and Kruskal-Wallis analysis of variance to study correlations and variability between groups. To characterize the population, we used cluster analysis with Ward’s linkage method. A positive correlation between iron with, ferritin and transferrin, and with hemoglobin was observed with the Spearman correlation. Kruskal-Wallis analysis of variance showed significant differences between these biomarkers in persons aged 0-29, 30-59 and over 60 years old. Cluster analysis, evidence low folate levels for population in general, and hemoglobin levels below the reference values for 42.8% of study population. Iron and vitamin B12 were within the reference range for most of the population. Low levels of the parameters were registered mainly in cardiovascular, gastrointestinal, neurological diseases and anemia patients.por
dc.identifier.urihttp://hdl.handle.net/10400.18/2460
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherInstituto Nacional de Saúde Doutor Ricardo Jorge, IPpor
dc.subjectComposição de Alimentospor
dc.subjectFolatospor
dc.subjectVitamin B12por
dc.subjectAnemiapor
dc.subjectCluster Analysispor
dc.titleCharacterization of a Population Concerning Vitamins and Anemia Biomarkerspor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlacePraga, República Checapor
oaire.citation.title14th International Nutrition & Diagnostics Conference (INDC), 2 - 5 September 2014por
rcaap.rightsrestrictedAccesspor
rcaap.typeconferenceObjectpor

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