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Carcinogenesis

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2014 chapter carcinogenesis.pdf2.03 MBAdobe PDF Download

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Abstract(s)

Cancer, or neoplasia, is a complex disease with multiple causes. Many intrinsic and extrinsic factors influence the development of cancer. Intrinsic or host factors include age, sex, genetic constitution, immune system function, metabolism, hormone levels, and nutritional status. Extrinsic factors include substances eaten, drunk, or smoked; workplace and environmental (air, water, and soil) exposures; natural and medical radiation exposure; sexual behavior; and elements of lifestyle such as social and cultural environment, personal behavior, and habits. Intrinsic and extrinsic factors can interact with one another to influence the development of cancer. In this article, we will discuss all the varied aspects of research that will ultimately lead to the prevention of cancer in man.

Description

This article is a revision of the previous edition article by David E. Malarkey and Robert R. Maronpot, volume 1, pp 445–466, 2005, Elsevier Inc.

Keywords

Cancer Environmental Toxicology Neoplasia Ar e Saúde Ocupacional Genotoxidade Ambiental e Ocupacional

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Citation

In: Wexler P. (Ed.). Encyclopedia of Toxicology. 3rd edition. vol 1. Elsevier Inc., Academic Press, pp. 713-29. ISBN: 9780123864543

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