Publication
Effects of stress exposure in captivity on physiology and infection in avian hosts: no evidence of increased Borrelia burgdorferi s.l. infectivity to vector ticks
| dc.contributor.author | Norte, A. C. | |
| dc.contributor.author | Araújo, P. M. | |
| dc.contributor.author | Augusto, L. | |
| dc.contributor.author | Guímaro, H. | |
| dc.contributor.author | Santos, S. | |
| dc.contributor.author | Lopes, R. J. | |
| dc.contributor.author | Núncio, M. S. | |
| dc.contributor.author | Ramos, J. A. | |
| dc.contributor.author | Lopes de Carvalho, I. | |
| dc.date.accessioned | 2023-03-20T11:07:12Z | |
| dc.date.available | 2023-03-20T11:07:12Z | |
| dc.date.issued | 2022-01 | |
| dc.description.abstract | Exposure to environmental stressors, an increasingly recurring event in natural communities due to anthropogenic-induced environmental change, profoundly impacts disease emergence and spread. One mechanism through which this occurs is through stress-induced immunosuppression increasing disease susceptibility, prevalence, intensity and reactivation in hosts. We experimentally evaluated how exposure to stressors affected both the physiology of avian hosts and the prevalence of the zoonotic bacteria Borrelia burgdorferi sensu lato (s.l.), in two model species-the blackbird Turdus merula and the robin Erithacus rubecula captured in the wild, using xenodiagnoses and analysis of skin biopsies and blood. Although exposure to stressors in captivity induced physiological stress in birds (increased the number of circulating heterophils), there was no evidence of increased infectivity to xenodiagnostic ticks. However, Borrelia detection in the blood for both experimental groups of blackbirds was higher by the end of the captivity period. The infectivity and efficiency of transmission were higher for blackbirds than robins. When comparing different methodologies to determine infection status, xenodiagnosis was a more sensitive method than skin biopsies and blood samples, which could be attributed to mild levels of infection in these avian hosts and/or dynamics and timing of Borrelia infection relapses and redistribution in tissues. | pt_PT |
| dc.description.sponsorship | This study received financial support from Fundação para a Ciência e a Tecnologia by the strategic programme of MARE (MARE - UID/MAR/04292/2020) and the fellowship (SFRH/BPD/108197/2015) and transitory norm contract DL57/2016/CP1370/CT89 to ACN, and the Portuguese National Institute of Health. PMA was funded by an investi gator contract from the project “PTDC/BIA-EVL/31569/2017 - NORTE -01-0145- FEDER-30288,” co-funded by NORTE2020 through Portugal 2020 and FEDER Funds, and by National Funds through FCT; RJL was funded by national funds (Transitory Norm contract DL57/2016/CP1440/ CT0006). | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Microb Ecol. 2022 Jan;83(1):202-215. doi: 10.1007/s00248-021-01738-3. Epub 2021 Mar 23. | pt_PT |
| dc.identifier.doi | 10.1007/s00248-021-01738-3 | pt_PT |
| dc.identifier.issn | 0095-3628 | |
| dc.identifier.uri | http://hdl.handle.net/10400.18/8563 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Springer | pt_PT |
| dc.relation | Borrelia burgdorferi s.l. interactions with vertebrate hosts and vectors – key factors affecting Borrelia maintenance in nature | |
| dc.relation | Genomics and quantitative genetics of vocal learning in birds | |
| dc.relation.publisherversion | https://link.springer.com/article/10.1007/s00248-021-01738-3 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
| dc.subject | Birds | pt_PT |
| dc.subject | Borrelia | pt_PT |
| dc.subject | Immunosuppression | pt_PT |
| dc.subject | Reservoir Host | pt_PT |
| dc.subject | Stress | pt_PT |
| dc.subject | Xenodiagnosis | pt_PT |
| dc.subject | Infecções Sistémicas e Zoonoses | pt_PT |
| dc.title | Effects of stress exposure in captivity on physiology and infection in avian hosts: no evidence of increased Borrelia burgdorferi s.l. infectivity to vector ticks | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | Borrelia burgdorferi s.l. interactions with vertebrate hosts and vectors – key factors affecting Borrelia maintenance in nature | |
| oaire.awardTitle | Genomics and quantitative genetics of vocal learning in birds | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMAR%2F04292%2F2020/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/OE/SFRH%2FBPD%2F108197%2F2015/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FBIA-EVL%2F31569%2F2017/PT | |
| oaire.citation.endPage | 215 | pt_PT |
| oaire.citation.issue | 1 | pt_PT |
| oaire.citation.startPage | 202 | pt_PT |
| oaire.citation.title | Microbial Ecology | pt_PT |
| oaire.citation.volume | 83 | pt_PT |
| oaire.fundingStream | 6817 - DCRRNI ID | |
| oaire.fundingStream | OE | |
| oaire.fundingStream | 9471 - RIDTI | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.embargofct | Acesso de acordo com política editorial da revista. | pt_PT |
| rcaap.rights | embargoedAccess | pt_PT |
| rcaap.type | article | pt_PT |
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