Publicação
New Delhi metallo-beta-lactamase 1-producing Enterobacteriaceae: emergence and response in Europe
| dc.contributor.author | Struelens, M. J. | |
| dc.contributor.author | Monnet, D. L. | |
| dc.contributor.author | Magiorakos, A. P. | |
| dc.contributor.author | O’Connor, F. Santos | |
| dc.contributor.author | Giesecke, J . | |
| dc.contributor.author | The European NDM-1 Survey Participants | |
| dc.date.accessioned | 2011-09-19T12:35:35Z | |
| dc.date.available | 2011-09-19T12:35:35Z | |
| dc.date.issued | 2010-11-18 | |
| dc.description | The European NDM-1 Survey Participants: Manuela Caniça (Departamento de Doenças Infecciosas do INSA) | por |
| dc.description.abstract | Acquired carbapenemases confer extensive antibiotic resistance to Enterobacteriaceae and represent a public health threat. A novel acquired carbapenemase, New Delhi metallo-beta-lactamase 1 (NDM-1), has recently been described in the United Kingdom and Sweden, mostly in patients who had received care on the Indian subcontinent. We conducted a survey among 29 European countries (the European Union Member States, Iceland and Norway) to gather information on the spread of NDM-1-producing Enterobacteriaceae in Europe, on public health responses and on available national guidance on detection, surveillance and control. A total of 77 cases were reported from 13 countries from 2008 to 2010. Klebsiella pneumoniae was the most frequently reported species with 54%. Among 55 cases with recorded travel history, 31 had previously travelled or been admitted to a hospital in India or Pakistan and five had been hospitalised in the Balkan region. Possible nosocomial acquisition accounted for 13 of 77 cases. National guidance on NDM-1 detection was available in 14 countries and on NDM-1 control in 11 countries. In conclusion, NDM-1 is spreading across Europe, where it is frequently linked to a history of healthcare abroad, but also to emerging nosocomial transmission. National guidance in response to the threat of carbapenemase-producing Enterobacteriaceae is available in approximately half of the surveyed European countries. Surveillance of carbapenemase- producing Enterobacteriaceae must be enhanced in Europe and effective control measures identified and implemented. | por |
| dc.identifier.citation | Euro Surveill. 2010 Nov 18;15(46). pii: 19716 | por |
| dc.identifier.issn | 1025-496X | |
| dc.identifier.uri | http://hdl.handle.net/10400.18/205 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | European Centre for Disease Prevention and Control | por |
| dc.relation.publisherversion | http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19716 | por |
| dc.subject | Beta-lactamase | por |
| dc.subject | Enterobacteriaceae | por |
| dc.subject | Resistência aos Antimicrobianos | por |
| dc.title | New Delhi metallo-beta-lactamase 1-producing Enterobacteriaceae: emergence and response in Europe | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.title | Eurosurveillance | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |