Publication
In vitro and intracellular antimycobacterial activity of a Bacillus pumilus strain
| dc.contributor.author | Hassi, Mohammed | |
| dc.contributor.author | David, Suzanna | |
| dc.contributor.author | Haggoud, Abdellatif | |
| dc.contributor.author | El Guendouzi, Souraya | |
| dc.contributor.author | El Ouarti, Asmae | |
| dc.contributor.author | Ibn Souda, Saad | |
| dc.contributor.author | Iraqui, Mohammed | |
| dc.date.accessioned | 2012-10-25T11:24:03Z | |
| dc.date.available | 2012-10-25T11:24:03Z | |
| dc.date.issued | 2012-01-25 | |
| dc.description.abstract | Despite the declaration of tuberculosis (TB) as a global emergency by the world health organization (WHO) about 20 years ago, the worldwide problem of this disease has worsened due to increased drug resistance of tuberculosis bacilli and acquired immune deficiency syndrome (AIDS) pandemic. Consequently, fight against multidrug and extensively drug-resistant TB is a high priority for public health and research. The present work describes the isolation of a Bacillus pumilus strain secreting a metabolite of protein nature capable of inhibiting mycobacterial growth (Mycobacterium smegmatis, Mycobacterium aurum and Mycobacterium bovis BCG). This metabolite is not toxic, accumulates within the macrophage and inactivates the bacilli with a comparable efficiency to that of the pure commercial antimycobacterial substance Amikacin. | por |
| dc.identifier.citation | African Journal of Microbiology Research 2012;6(10):2299-2304 | por |
| dc.identifier.issn | 1996-0808 | |
| dc.identifier.other | doi:10.5897/AJMR11.1021 | |
| dc.identifier.uri | http://hdl.handle.net/10400.18/1069 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Academic Journals | por |
| dc.relation.publisherversion | http://www.academicjournals.org/AJMR | por |
| dc.subject | Drug Resistance of Tuberculosis Bacilli | por |
| dc.subject | Mycobacteria | por |
| dc.subject | Antimycobacterial Agents | por |
| dc.subject | Bacillus Pumilus | por |
| dc.subject | Resistência aos Antimicrobianos | por |
| dc.title | In vitro and intracellular antimycobacterial activity of a Bacillus pumilus strain | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 2304 | por |
| oaire.citation.startPage | 2299 | por |
| oaire.citation.volume | 6 | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |