Repository logo
 
Publication

Labial lesion in a Portuguese man returned from Brazil - The role of molecular diagnosis

2018-03Journal article Restricted access
Simple item page
dc.contributor.authorFerreira, António
dc.contributor.authorSilva, Augusta
dc.contributor.authorCruz, Mariana
dc.contributor.authorSabino, Raquel
dc.contributor.authorVeríssimo, Cristina
dc.date.accessioned2018-02-27T17:06:27Z
dc.date.available2019-12-01T01:30:13Z
dc.date.issued2018-03
dc.description.abstractParacoccidioidomycosis is an acute - to chronic systemic mycosis caused by the fungus Paracoccidioides. Two species are recognized as causing paracoccidioidomycosis: Paracoccidioides brasiliensis and Paracoccidioides lutzii. Paracoccidioidomycosis is a commonly diagnosed fungal infection in South America and rare in Europe. Nevertheless, with the increase of immigration from endemic regions to European countries, clinicians must be aware of tropical infections and strongly consider them in differential diagnosis, having therefore the knowledge of all the available means necessary to identify specific pathogens. The authors present a case report of a Portuguese 46-year-old man who lived in Itaipava-Brazil for the past 21 years. In his return to Portugal, presented a lip lesion, weight loss, pulmonary infiltrates and cavities, and generalized adenopathies. An histopatologic diagnosis of mucocutaneous and pulmonary cryptococcosis was initially made. However, the negative result of cryptococcal antigen and the patient's epidemiology lead to the hypothesis of other etiological agent. All cultural examinations were negative, however the molecular detection of fungal DNA directly from tissue samples allowed the identification of the correct etiological agent as Paracoccidioides brasiliensis and the introduction of a most effective treatment for the management of this fungal infection. This was the first time that Paracoccidioides brasiliensis was identified by this PCR technique in Portugal.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationTravel Med Infect Dis. 2018 Mar - Apr;22:80-81. doi: 10.1016/j.tmaid.2017.12.001. Epub 2017 Dec 6.pt_PT
dc.identifier.doi10.1016/j.tmaid.2017.12.001pt_PT
dc.identifier.issn1477-8939
dc.identifier.urihttp://hdl.handle.net/10400.18/5095
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://doi.org/10.1016/j.tmaid.2017.12.001pt_PT
dc.subjectParacoccidioidomycosispt_PT
dc.subjectPolymerase Chain Reactionpt_PT
dc.subjectHuman Migrationpt_PT
dc.subjectPorttugalpt_PT
dc.subjectInfecções Sistémicas e Zoonosespt_PT
dc.titleLabial lesion in a Portuguese man returned from Brazil - The role of molecular diagnosispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleTravel Medicine and Infectious Diseasept_PT
rcaap.rightsembargoedAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Artigo em press Paracoccidioides.pdf
Size:
220.81 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

DDI - Artigos em revistas internacionais