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Glycosyl flavonoids from Salvia sclareoides: contribution to the development of a new functional food

dc.contributor.authorAbraços, L.
dc.contributor.authorMartins, A.
dc.contributor.authorNeng, N.
dc.contributor.authorNogueira, J.M.F.
dc.contributor.authorSerralheiro, M.L.
dc.contributor.authorBatista, A.P.
dc.contributor.authorRaymundo, A.
dc.contributor.authorSousa, I.
dc.contributor.authorAlbuquerque, T.G.
dc.contributor.authorCosta, H.S.
dc.contributor.authorRauter, A.P.
dc.date.accessioned2019-03-08T19:06:19Z
dc.date.available2019-03-08T19:06:19Z
dc.date.issued2018-07
dc.description.abstractSalvia sclareoides is a plant of spontaneous Portuguese vegetation that has relevant properties, as part of its cholinergic action and in the prevention of the formation of amyloid plaques. Previous studies suggested [1,2] that this species of Salvia can be used as a functional food and also in the development of a food supplement in the context of the prevention and treatment of Alzheimer's disease. Sweet cookies were developed with different concentrations (2 % and 5 %) of S. sclareoides, previously ground for particle size reduction (2.00 mm). The nutritional composition was determined, namely: moisture content, ash, total protein, total fat, dietary fibre and salt [3]. The available carbohydrates and the energy value were obtained by calculation. Extracts were prepared from the dried aerial parts of the plant. Different extraction methodologies were used and the phenolic profile of each extract was determined by high performance liquid chromatography with diode array detection. The antioxidant and anticholinesterase activities of these extracts were also evaluated. The ethanol extract of S. sclareoides, with 2.00 mm grain size, presented the highest concentration of phenolic compounds (143.74 mg GAE/g dry extract) and antioxidant activity (68.45 %), while the aqueous extract showed the best anticholinesterase activity (30.86 %). The glycosylated flavonoids rutin and (7-O-glucosyl)luteolin are clearly the major constituents present in all extracts, along with epicatechin, ellagic acid and (7-O-glucosyl)naringenin.pt_PT
dc.description.sponsorshipTânia Gonçalves Albuquerque thanks the PhD Scholarship (SFRH/BD/99718/2014), funded by FCT, FSE and MEC.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/6141
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectComposição dos Alimentospt_PT
dc.subjectNutrição Aplicadapt_PT
dc.subjectSalvia Sclareoidespt_PT
dc.subjectFunctional Foodpt_PT
dc.subjectAlzheimer's Diseasept_PT
dc.titleGlycosyl flavonoids from Salvia sclareoides: contribution to the development of a new functional foodpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceLisboa, Portugalpt_PT
oaire.citation.titleInternational Carbohydrate Symposium, 14-19 julho 2018pt_PT
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT

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