System Biology Approach for Cardiovascular Medicine

Mariano, Cibelle; Antunes, Marília; Bourbon, Mafalda

http://hdl.handle.net/10400.18/3332

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Authors

Mariano, Cibelle

Antunes, Marília

Bourbon, Mafalda

Abstract(s)

Objetives: This research project proposes the study of associaSons and/or interacions between genetic, non-genetic and environmental factors and its effects on a very important dyslipidaemia marker, apolipoprotein B (apoB) levels, by modelling genetic predisposition, biological and environmental components (such as lifestyle and behavioral variables) with apoB serum levels. It is also proposed the characterizacion of the lipid and genetic cardiovascular risk profiles of the Portuguese populacion, as well as the correlaSon between dyslipidaemia and other cardiovascular risks and biochemical markers.