Repository logo
 
Publication

Excess pneumonia and influenza hospitalizations associated with influenza epidemics in Portugal from season 1998/1999 to 2014/2015

2018-02-19Journal article Open access
Simple item page
dc.contributor.authorRodrigues, Emanuel
dc.contributor.authorMachado, Ausenda
dc.contributor.authorSilva, Susana
dc.contributor.authorNunes, Baltazar
dc.date.accessioned2019-03-08T16:01:14Z
dc.date.available2019-03-08T16:01:14Z
dc.date.issued2018-02-19
dc.description.abstractBackground: The aim of this study was to estimate excess pneumonia and influenza (P&I) hospitalizations during influenza epidemics and measure their correlation with influenza vaccine coverage in the 65 and more years old, according to the type/subtype of influenza virus. Methods: The study period comprised week 40/1998-40/2015. Age-specific weekly P&I hospitalizations (ICD-9: 480-487) as main diagnosis were extracted from the National Hospital Discharge database. Age-specific baseline hospitalization rates were estimated by autoregressive integrated moving average (ARIMA) model without time periods with excess hospitalizations. Excess hospitalizations were calculated by subtracting expected hospitalization rates from the observed during influenza epidemic periods. Correlation between excess P&I hospitalizations and influenza vaccine coverage in the elderly was measured with Pearson correlation coefficient. Results: The average excess P&I hospitalizations/season was 19.4/105 (range 0-46.1/105), and higher excess was observed in young children with <2 years (79.8/105) and ≥65 years (68.3/105). In epidemics with A(H3) dominant, the highest excess hospitalizations were observed among 65 and over. Seasons which influenza B or A(H1)pdm09 dominance the highest excess was observed in children with <2 years. High negative correlation was estimated between excess hospitalizations associated with A(H3) circulation and vaccine coverage in the elderly (r = −.653; 95% CI: −0.950 to −0.137). Conclusion: Over 80% of the influenza epidemics were associated with excess hospitalizations. However, excess P&I hospitalizations pattern differed from age group and circulating virus. This ecologic approach also identified a reduction in excess P&I associated with A(H3) circulation with increasing vaccine coverage in the elderly.pt_PT
dc.description.sponsorshipAPC for this article is funded by World Health Organization (WHO)pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInfluenza Other Respir Viruses. 2018 feb;12(1):153-160. doi: 10.1111/irv.12501pt_PT
dc.identifier.doi10.1111/irv.12501pt_PT
dc.identifier.issn1750-2640
dc.identifier.urihttp://hdl.handle.net/10400.18/6105
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/doi/full/10.1111/irv.12501pt_PT
dc.subjectAutoregressive Integrated Moving Average Modelspt_PT
dc.subjectExcess Hospitalizationspt_PT
dc.subjectInfluenza Epidemicspt_PT
dc.subjectVaccine Coveragept_PT
dc.subjectEstados de Saúde e de Doençapt_PT
dc.titleExcess pneumonia and influenza hospitalizations associated with influenza epidemics in Portugal from season 1998/1999 to 2014/2015pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage160pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage153pt_PT
oaire.citation.titleInfluenza and Other Respiratory Virusespt_PT
oaire.citation.volume12pt_PT
person.familyNameMachado
person.familyNamedas Neves Pereira da Silva
person.familyNameNunes
person.givenNameAusenda
person.givenNameSusana
person.givenNameBaltazar
person.identifier.ciencia-id1217-6076-5D88
person.identifier.ciencia-idB718-8EF6-EBD8
person.identifier.ciencia-idAB11-AD48-A8DF
person.identifier.orcid0000-0002-1849-1499
person.identifier.orcid0000-0003-2524-0548
person.identifier.orcid0000-0001-6230-7209
person.identifier.scopus-author-id9133723200
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication544ad266-0c22-4a50-9ebc-86acc08d6666
relation.isAuthorOfPublication49b180bc-3e03-4347-9e32-5725fd7142f8
relation.isAuthorOfPublicationbe4efa0d-49df-4a93-bfdd-b76d9f7bf492
relation.isAuthorOfPublication.latestForDiscoverybe4efa0d-49df-4a93-bfdd-b76d9f7bf492

Files

Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
IRV-12-153.pdf
Size:
545.21 KB
Format:
Adobe Portable Document Format
Download
Thumbnail Image
Name:
IRV-12-153-s001.pdf
Size:
200.5 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

DEP - Artigos em revistas internacionais