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LOCUS (LOng Covid-Understanding Symptoms, events and use of services in Portugal): A three-component study protocol

2023-04-26Journal article Open access
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dc.contributor.authorDinis Teixeira, J.P.
dc.contributor.authorSantos, Mário J.D.S.
dc.contributor.authorSoares, Patricia
dc.contributor.authorAzevedo, Luísa de
dc.contributor.authorBarbosa, Patrícia
dc.contributor.authorBoas, Andreia Vilas
dc.contributor.authorCordeiro, João V.
dc.contributor.authorDias, Sónia
dc.contributor.authorFonseca, Marta
dc.contributor.authorGoes, Ana Rita
dc.contributor.authorLobão, Maria João
dc.contributor.authorMoniz, Marta
dc.contributor.authorNóbrega, Sofia
dc.contributor.authorPeralta-Santos, André
dc.contributor.authorRamos, Víctor
dc.contributor.authorRocha, João Victor
dc.contributor.authorda Silva, António Carlos
dc.contributor.authorBrazão, Maria da Luz
dc.contributor.authorLeite, Andreia
dc.contributor.authorNunes, Carla
dc.date.accessioned2023-10-13T08:53:23Z
dc.date.available2023-10-13T08:53:23Z
dc.date.issued2023-04-26
dc.descriptionStudy Protocolpt_PT
dc.description.abstractApproximately 10% of patients experience symptoms of Post COVID-19 Condition (PCC) after a SARS-CoV-2 infection. Akin acute COVID-19, PCC may impact a multitude of organs and systems, such as the cardiovascular, respiratory, musculoskeletal, and neurological systems. The frequency and associated risk factors of PCC are still unclear among both community and hospital settings in individuals with a history of COVID-19. The LOCUS study was designed to clarify the PCC’s burden and associated risk factors. LOCUS is a multi-component study that encompasses three complementary building blocks. The “Cardiovascular and respiratory events following COVID-19” component is set to estimate the incidence of cardiovascular and respiratory events after COVID-19 in eight Portuguese hospitals via electronic health records consultation. The “Physical and mental symptoms following COVID-19” component aims to address the community prevalence of self-reported PCC symptoms through a questionnaire-based approach. Finally, the "Treating and living with Post COVID-19 Condition" component will employ semi-structured interviews and focus groups to characterise reported experiences of using or working in healthcare and community services for the treatment of PCC symptoms. This multi-component study represents an innovative approach to exploring the health consequences of PCC. Its results are expected to provide a key contribution to the optimisation of healthcare services design.pt_PT
dc.description.sponsorshipThis study is sponsored by Pfizer (grant code #68639655).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPLoS One. 2023 Apr 26;18(4):e0285051. doi: 10.1371/journal.pone.0285051. eCollection 2023.pt_PT
dc.identifier.doi10.1371/journal.pone.0285051pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/8724
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherPublic Library of Sciencept_PT
dc.relation.publisherversionhttps://doi.org/10.1371/journal.pone.0285051pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectCOVID-19pt_PT
dc.subjectPost COVID-19 Conditionpt_PT
dc.subjectSARS-CoV-2 Infectionpt_PT
dc.subjectCondição pós-COVID-19pt_PT
dc.subjectEstados de Saúde e de Doençapt_PT
dc.subjectInfecções Respiratóriaspt_PT
dc.subjectPortugalpt_PT
dc.titleLOCUS (LOng Covid-Understanding Symptoms, events and use of services in Portugal): A three-component study protocolpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue4pt_PT
oaire.citation.startPagee0285051pt_PT
oaire.citation.titlePLoS Onept_PT
oaire.citation.volume18pt_PT
person.familyNameSoares
person.familyNameLeite
person.givenNamePatricia
person.givenNameAndreia
person.identifier1050496
person.identifier1052436
person.identifier.ciencia-id0415-632D-8609
person.identifier.ciencia-id2F10-F9A9-E8A7
person.identifier.orcid0000-0001-5033-9115
person.identifier.orcid0000-0003-0843-0630
person.identifier.scopus-author-id52063758300
person.identifier.scopus-author-id57109931300
rcaap.embargofctAcesso de acordo com política editorial da revistapt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationdf1b8bab-1e35-4561-92d0-8aeb17371a29
relation.isAuthorOfPublication838ff85b-16c9-4992-b13f-e3099f916717
relation.isAuthorOfPublication.latestForDiscovery838ff85b-16c9-4992-b13f-e3099f916717

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