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Assessment of a Portuguese panel reactive antibody calculator

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Abstract(s)

Calculated panel-reactive antibody (cPRA) is an accurate measure for the definition of candidates’ immunization to a transplant. Based upon unacceptable HLA antigens to which the patient has been sensitized, cPRA is computed with HLA allelic and haplotypic frequencies from a pool of possible donors and represents the percentage of donors that express one or more of the antigens unacceptable for a given transplant candidate. The aim of this study is to compare cPRA values obtained from HLA frequencies of Portuguese donors with values obtained from cPRA calculators from international established sources.

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Keywords

Panel-reactive Antibody Calculator Calculated Panel-reactive Antibody (cPRA) Portuguese Panel Reactive Antibody Calculator Transplants Portuguese Donors

Pedagogical Context

Citation

HLA: Immune Response Genetics. 2018;91(5):354-474. (Special Issue: Abstracts for the 32nd European Immunogenetics and Histocompatibility Conference and the 25th Annual Meeting of the Italian Society for Immunogenetics and Transplantation Biology (AIBT) Venice Lido, Italy May 9–12, 2018)

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John Wiley & Sons Ltd/ European Federation for Immunogenetics

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