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Prevalence of congenital heart defects in Europe, 2008-2015: A registry‐based study

2022-12-01Journal article Open access
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dc.contributor.authorMamasoula, Chrysovalanto
dc.contributor.authorAddor, Marie‐Claude
dc.contributor.authorCarbonell, Clara Cavero
dc.contributor.authorMatias Dias, Carlos
dc.contributor.authorEchevarría‐González‐de‐Garibay, Luis‐Javier
dc.contributor.authorGatt, Miriam
dc.contributor.authorKhoshnood, Babak
dc.contributor.authorKlungsoyr, Kari
dc.contributor.authorRandall, Kay
dc.contributor.authorStoianova, Sylvia
dc.contributor.authorHaeusler, Martin
dc.contributor.authorNelen, Vera
dc.contributor.authorNeville, Amanda J.
dc.contributor.authorPerthus, Isabelle
dc.contributor.authorPierini, Anna
dc.contributor.authorBertaut‐Nativel, Bénédicte
dc.contributor.authorRissmann, Anke
dc.contributor.authorRouget, Florence
dc.contributor.authorSchaub, Bruno
dc.contributor.authorTucker, David
dc.contributor.authorWellesley, Diana
dc.contributor.authorZymak‐Zakutnia, Natalya
dc.contributor.authorBarisic, Ingeborg
dc.contributor.authorde Walle, Hermien E.K.
dc.contributor.authorLanzoni, Monica
dc.contributor.authorMullaney, Carmel
dc.contributor.authorPennington, Lindsay
dc.contributor.authorRankin, Judith
dc.date.accessioned2023-01-09T14:22:33Z
dc.date.available2023-01-09T14:22:33Z
dc.date.issued2022-12-01
dc.description.abstractBackground: The total prevalence of congenital heart defects (CHDs) varies by populations and over time. Studies that examine trends in the prevalence of CHD in different regions may shed light on our understanding of the occurrence of CHD and the impact of different risk factors. Objectives: To examine trends in total and live birth prevalence of nonsyndromic CHD in Europe between the years 2008 and 2015 and to investigate if the decreasing trend reported by previous studies is continuing. Methods: Cases of CHD delivered between January 1, 2008 and December 31, 2015 notified to 25 population-based EUROCAT (European Surveillance of Congenital Anomalies) registries in 14 countries, formed the population-based case-series. Prevalence (total/live) rates and 95% confidence intervals were calculated as the number of cases per 10,000 births (live and stillbirths). Time trends in prevalence of all nonsyndromic CHDs and for three CHD severity groups (very severe, severe, and less severe) were plotted using a Poisson regression multilevel approach. Results: The total prevalence of nonsyndromic CHD was 57.1 per 10,000 births (live births and stillbirths) for the 8-year period and remained stable across the three CHD severity groups while the live birth prevalence was 60.2 per 10,000 births. There was considerable variation in the reported total CHD prevalence and the direction of trends by registry. A decreasing prevalence ofCHD was observed for the Norway and England/Wales registries, whereas the CHD prevalence increased for registries in Italy and Croatia. Conclusions: The total prevalence of CHD in Europe between the years 2008 and 2015 remained stable for all CHD and across the three CHD severity groups. The decreasing trend reported by previous studies has not continued. However, we found significant differences in the total and live birth prevalence by registry.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBirth Defects Res . 2022 Dec 1;114(20):1404-1416. doi: 10.1002/bdr2.2117. Epub 2022 Nov 8.pt_PT
dc.identifier.doi10.1002/bdr2.2117pt_PT
dc.identifier.issn2472-1727
dc.identifier.urihttp://hdl.handle.net/10400.18/8406
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWiley/ Birth Defects Researchpt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/doi/10.1002/bdr2.2117pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectCongenital Anomaliespt_PT
dc.subjectHeart Defectspt_PT
dc.subjectEUROCATpt_PT
dc.subjectEuropean Surveillance of Congenital Anomaliespt_PT
dc.subjectCongenital Heart Diseasept_PT
dc.subjectPrevalence Ratept_PT
dc.subjectEuropept_PT
dc.subjectRegisto Nacional de Anomalias Congénitaspt_PT
dc.subjectRENACpt_PT
dc.subjectObservação em Saúde e Vigilânciapt_PT
dc.subjectEstados de Saúde e de Doençapt_PT
dc.subjectPortugalpt_PT
dc.titlePrevalence of congenital heart defects in Europe, 2008-2015: A registry‐based studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1416pt_PT
oaire.citation.issue20pt_PT
oaire.citation.startPage1404pt_PT
oaire.citation.titleBirth Defects Researchpt_PT
oaire.citation.volume114pt_PT
person.familyNameMatias Dias
person.givenNameCarlos
person.identifier.ciencia-id6311-6117-ADEB
person.identifier.orcid0000-0002-0206-5874
person.identifier.ridI-6335-2012
person.identifier.scopus-author-id23103292400
rcaap.embargofctAcesso de acordo com página web do editor da revista.pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationfe9524e7-fc22-42f6-8eca-ab6a513ddd6b
relation.isAuthorOfPublication.latestForDiscoveryfe9524e7-fc22-42f6-8eca-ab6a513ddd6b

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