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Authors
Advisor(s)
Abstract(s)
Human health is constantly affected by a multitude of agents present in the surrounding environment. Biomarkers are key factors, both in clinical health risk assessment and in environmental risk assessment. Traditionally, they are classified in three different classes: exposure, effect, and susceptibility. Their main usefulness relies on their ability to link hazard exposure to the pathogenesis of human disease. The development and validation of biomarkers as early predictors of clinical disease is a top priority, improving health risk assessment and contributing to new disease prevention policies in environmental and occupational settings.
Description
Keywords
Biomarkers Human Health Risk Assessment Environmental Exposure Biological Monitoring Environmental Monitoring Genetic susceptibility Internal Dose Molecular Epidemiology Mutation Assays Occupational Exposure Risk Assessment Genotoxidade Ambiental
Pedagogical Context
Citation
In: Wexler P. (Ed.). Encyclopedia of Toxicology. 3rd edition. vol 1. Elsevier Inc., Academic Press, pp. 479-82. ISBN: 9780123864543
Publisher
Elsevier Inc., Academic Press