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Mycotoxins under the Human Biomonitoting Initiative (HBM4EU): challenges in the near future

dc.contributor.authorAlvito, Paula
dc.contributor.authorVasco, Elsa
dc.contributor.authorAssunção, Ricardo
dc.contributor.authorMartins, Carla
dc.contributor.authorLouro, H.
dc.contributor.authorNamorado, S.
dc.contributor.authorViegas, S.
dc.contributor.authorSilva, MJ
dc.date.accessioned2021-03-10T08:27:55Z
dc.date.available2021-03-10T08:27:55Z
dc.date.issued2020-11-11
dc.description.abstractMycotoxins are natural toxins produced by several fungi genera that contaminate cereals, fruits and other food. The ingestion of contaminated food and feed may result not only in acute disease but also in chronic conditions, e.g., reproductive toxicity, inflammatory bowel diseases or cancer either in animals or humans. It is thus of high relevance to use a one health approach to monitor environmental, human and animal exposure to mycotoxins and their effects, in order to decrease mycotoxins-associated outcomes. In the Human Biomonitoring Initiative (HBM4EU, https://www.hbm4eu.eu/the-project/), following a systematic prioritization exercise which brought together national and EU level policy needs for knowledge on chemical exposure and health outcomes, mycotoxins (Deoxynivalenol and Fumonisin B1) were considered as priority substances around which the HBM4EU research programme is being developed. Within the three pillars of the HBM4EU, namely, 1. Science to Policy, 2. European HBM Platform and 3. Exposure and Health, answers to several identified policy questions related to mycotoxins exposure and effects are being debated, including the current levels of human exposure and time trends in Europe, geographical differences and highly exposed subgroups (including workers), the availability of toxicokinetics data, methods for analyzing mycotoxins and their metabolites in human samples, the potential for using effect biomarkers, the use of biomonitoring data under a risk assessment framework, derivation of HBM guidance values. During this presentation, challenges related to those questions and human biomonitoring of mycotoxins will be presented and discussed in the perspective of a one health approach.pt_PT
dc.description.sponsorshipWork co-funded by the HBM4EU project, Grant Agreement No: 733032 and by national funds: FCT/MEC - FEDER, within the PT2020 Partnership Agreement and Compete 2020 through CESAM (UIDP/50017/2020+UIDB/50017/2020) and ToxOmics (UIDB/00009/2020).pt_PT
dc.description.versionN/Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/7393
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationEuropean Human Biomonitoring Initiative
dc.relationCentre for Environmental and Marine Studies
dc.relationCentre for Environmental and Marine Studies
dc.relationCentre for Toxicogenomics and Human Health
dc.subjectMicotoxinaspt_PT
dc.subjectBiomonitorização Humanapt_PT
dc.subjectSegurança Alimentarpt_PT
dc.subjectAvaliação do Riscopt_PT
dc.subjectToxicologiapt_PT
dc.titleMycotoxins under the Human Biomonitoting Initiative (HBM4EU): challenges in the near futurept_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleEuropean Human Biomonitoring Initiative
oaire.awardTitleCentre for Environmental and Marine Studies
oaire.awardTitleCentre for Environmental and Marine Studies
oaire.awardTitleCentre for Toxicogenomics and Human Health
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/733032/EU
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50017%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50017%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00009%2F2020/PT
oaire.citation.conferencePlaceAveiro, Portugal (online)pt_PT
oaire.citation.titleOne Health Day, Emerging Diseases, University of Aveiro, 11 Nov 2020pt_PT
oaire.fundingStreamH2020
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameEuropean Commission
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsclosedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isProjectOfPublication6815dc2d-ef7e-4535-8dd3-5193c8bffba5
relation.isProjectOfPublication4e22de31-8fc5-4b15-b980-3fd0edf5515d
relation.isProjectOfPublication0e72e6c8-b610-43e0-931c-8ad275ad6093
relation.isProjectOfPublicationa438b9d1-8a6a-4c90-a13b-7ccf34071451
relation.isProjectOfPublication.latestForDiscovery6815dc2d-ef7e-4535-8dd3-5193c8bffba5

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