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State of the art of the analytical methods for bisphenol A determination as result of its migration from polycarbonate

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Polycarbonate is a type of hard plastic, with high transparency, strength and durability, which is used in the manufacture of packaging and containers for food and beverages. 2,2-bis(4-hydroxyphenyl) propane, commonly known as bisphenol A (BPA), is a monomer made by reaction of phenol and acetone, and is mainly used in the production of polycarbonate and epoxy resins, although it can also be used as an additive in recycled paper and dental sealants. Although polycarbonate plastics are considered stable, BPA can migrate from these containers. Migration of BPA is increased when the packages are hydrolyzed at high temperature and neutral to alkaline pH. BPA is a widespread endocrine disruptor and has an estrogenic activity, therefore, there is a growing interest in the determination of this substance, especially in foodstuffs. According to the Regulation (EU) No 10/2011 on plastic materials and articles intended to come into contact with food, the specific migration limit (SML) applicable to BPA is 0.6 mg/kg. However, according to the Commission Directive 2011/8/EU of 28 January 2011, BPA is prohibited for the manufacture of polycarbonate infant feeding bottles. This review aims to identify the most commonly used analytical methods to determine the specific migration of BPA from polycarbonate materials and to compare the migration levels found in different studies, in recent years. The potential health problems related with BPA migration from food contact materials into foods were also assessed.

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Segurança Alimentar Polycarbonate Bbisphenol A Specific Migration Endocrine Disruptor

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